| Japanese |
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| Title | 99mTc-DTPA腎摂取率による腎機能算出法 (Gates法) の再評価 |
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| Subtitle | 原著 |
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| Authors | 伊藤和夫*, 荒川政憲** |
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| Organization | *北海道大学医学部核医学講座, **泌尿器科学講座 |
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| Journal | 核医学 |
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| Volume | 24 |
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| Number | 4 |
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| Page | 389-396 |
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| Year/Month | 1987/4 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」99mTc-DTPAの腎摂取率(%TRU)からクレアチニンクリアランス(Ccr)を算出するGates法に関して検討した. 1)日本人で求めた体重(W)と身長(H)の比(W/H)とCTスキャンで計測した腎の深さ(cm)との間には以下の回帰式が得られた. 両腎の右=13.6361・(W/H)0.6996(n=217, r=0.8661, p<0.001) 両腎の左=14.0285・(W/H)0.7554(n=224, r=0.8822, p<0.001) 片腎の右=17.2822・(W/H)0.8099(n=27, r=0.9515, p<0.01) 片腎の左=14.7577・(W/H)0.6997(n=21, r=0.9213, p<0.01) 2)%TRUとCcrとの間には以下の回帰式が得られた. W/Hから算出した腎の深さを用いた場合, Ccr=13.15・%TRU0.787(n=86, r=0.820, p<0.01)で, CTスキャンで実測した腎の深さを用いた場合には, Ccr=16.47・%TRU0.753(n=40, r=0.754)であった. Gates法は検査終了と同時に総腎機能ならびに分腎機能を評価できる簡便な検査法である. しかし, %TRUから糸球体濾過(GFR)を求める場合, Gates式は測定方法により異なるため, 各施設の検査の実情に即した回帰式の検討が必要である. |
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| Practice | 臨床医学：一般 |
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| Keywords | Kidney, Glomerular filtration rate (GFR), 99mTc-DTPA, Renal uptake, Renal depth. |
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| English |
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| Title | Re-estimation of Renal Function with 99mTc-DTPA by the Gates' Method |
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| Subtitle | Original Articles |
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| Authors | Kazuo ITOH*, Masanori ARAKAWA** |
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| Organization | *Department of Nuclear Medicine, **Department of Urology, Hokkaido University School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 24 |
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| Number | 4 |
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| Page | 389-396 |
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| Year/Month | 1987/4 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary]We analyzed a regression equation between percent total renal uptake (%TRU) of 99mTc-DTPA and creatinine clearance (Ccr) by the Gates' method in 82 patients. 1) The following regression equations between measured renal depth on CT scan and (weight in kg)/(height in cm) in Japanese were obtained; Right in both kidneys=13.6361・(W/H)0.6996 (n=217, r=0.86691, p<0.001) Left in both kidneys =14.0285・(W/H)0.7554 (n=224, r=0.8822, p<0.001) Right in single kidney=17.2882.(W/H)0.8099 (n=27, r=0.9515, p<0.01) Left in single kidney=14.7577.(W/H)0.6997 (n=21, r=0.9213, p<0.01) 2) Two regression equations between %TRU and Ccr were obtained. When calculated renal depth was adopted, regression equation was Ccr (ml/min, 1.48 m2)=13.15・%TRU0.787 (n=86, r=0.820, p<0.001). If measured renal depth on CT scan was used, regression equation was Ccr=16.47・%TRU0.753 (n=40, r=0.754). The Gates' method is very convenient for an immediate estimation of glomerular filtration rate (GFR) after renal scintigraphy using 99mTc-DTPA. However, the correlation coefficient was not high as compared to the Gates' results. The equation which was reported by Gates is not necessarily adaptable in routine study. Each facility which uses the Gates' method for estimating GFR should obtain the corrected regression equation between %TRU and Ccr. |
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| Practice | Clinical medicine |
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| Keywords | Kidney, Glomerular filtration rate (GFR), 99mTc-DTPA, Renal uptake, Renal depth. |
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