| Japanese |
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| Title | 運動負荷201Tl心筋SPECT像の定量的評価法 - 臨床的有用性の検討 - |
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| Subtitle | 原著 |
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| Authors | 土井修*, 山本修三**, 光藤和明*, 藤野俊夫*, 松永和夫*, 西原祥浩*, 阿波純二*, 後藤剛*, 長谷敏明*, 金万石*, 門田一繁*, 坂本貴昭*, 戸田晶子*, 河原泰人**, 重康牧夫** |
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| Authors(kana) | |
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| Organization | *倉敷中央病院循環器内科, **放射線科 |
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| Journal | 核医学 |
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| Volume | 24 |
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| Number | 3 |
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| Page | 279-287 |
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| Year/Month | 1987/3 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」運動負荷201Tl心筋SPECTの同心円表示法(CCD)にスライス数の基準化や回転補正等の改良を加え, その臨床的有用性を検討した. 対象は狭心症(AP)65例, 心筋梗塞症(MI)47例, 正常者55例である. 正常下限以下の点の個数Defect Score(DS)を求めた. DSによるCADの検出のSensitivityは, 83%(AP), 100%(MI), Specificityは69%であった. 視覚評価(おのおの77%, 98%, 83%)と比較し, ほぼ同等の結果であった. CCDはその客観性を考えれば, CADの検出および評価に有用な方法であると考えられた. 「I. はじめに」運動負荷201Tl心筋シンチは, 非観血的に心筋の血流分布を把握できるため虚血性心疾患の診断や, 経過観察等に広く利用されている. 特に近年Single Photon Emission CT(以下SPECT)が導入され, 病変の検出や広がりの評価が比較的容易になり, ますますその有用性が高まってきている. |
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| Practice | 臨床医学：一般 |
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| Keywords | Quantitative analysis of thallium-201 SPECT, Diagnosis of CAD, Quantification of Myocardial infarct size, Circumferential profile analysis. |
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| English |
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| Title | Quantitative Evaluation of Thallium-201 Myocardial Single Photon Emission CT (SPECT) : Clinical Application |
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| Subtitle | Original Articles |
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| Authors | Osamu DOI*, Shuzo YAMAMOTO**, Kazuaki MITSUDO*, Toshio FUJINO*, Kazuo MATSUNAGA*, Yoshihiro NISHIHARA*, Junji AWA*, Tsuyoshi GOTO*, Toshiaki HASE*, Manseki KIN*, Kazushige KADOTA*, Takaaki SAKAMOTO*, Masako TODA*, Yasuji KAWAHARA**, Makio SHIGEYASU** |
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| Authors(kana) | |
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| Organization | *Department of Cardiology, **Department of Radiology, Kurashiki Central Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 24 |
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| Number | 3 |
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| Page | 279-287 |
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| Year/Month | 1987/3 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary]We developed a new method for the quantitative evaluation of Tl-201 myocardial SPECT. Circumferential profile analysis was performed on the short axial slices from the apex to the base. Derived profile curves were changed into 9 curves by interpolation. The data were displayed on 9 concentric circles, providing Concentric Circular Display (CCD). From twenty subjects with normal coronary arteriography mean and standard deviation (SD) were calculated at each points of the 9 curves. Defect score (DS) was the number of points below mean-2 SD of the normal values. CCD analysis by the criterion of DS (>= 9) was compared with visual analysis (VA) in detect-ability of coronary artery disease (CAD). In AP (n=65) sensitivity was 83 % and 77 % in CCD and VA, respectively, while 100 % and 98% in MI (n=47). Specificity was 69 % and 83 % in normal subjects (n=35). Detectability of individual coronary artery lesions was 76% vs. 71 % for LAD and 84% vs. 75 % for RCA & LCX. Specificity was 64% vs. 92% (p<0.05) for LAD and 60% vs. 73% for RCA & LCX. Specificity of CCD was slightly inferior to that of visual analysis. In conclusion three dimensional information of myocardial SPECT was displayed in a two dimensional image by CCD and this makes it possible to evaluate myocardial perfusion easily and objectively. |
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| Practice | Clinical medicine |
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| Keywords | Quantitative analysis of thallium-201 SPECT, Diagnosis of CAD, Quantification of Myocardial infarct size, Circumferential profile analysis. |
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