| Japanese |
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| Title | 67Ga-citrateの肺門集積の研究 - 喫煙と肺門集積との関係 - |
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| Subtitle | 原著 |
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| Authors | 周藤裕治* |
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| Organization | *鳥取大学医学部放射線医学教室 |
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| Journal | 核医学 |
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| Volume | 24 |
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| Number | 3 |
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| Page | 235-244 |
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| Year/Month | 1987/3 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」67Ga-citrateの肺門集積の機序について, 胸部X線写真上あるいは臨床上肺に異常を認めない103例の67Gaシンチグラムの肺門部に対して喫煙歴を主に肉眼的解析および定量的解析を行うとともに, 喫煙負荷実験を施行し, RIカウント比の測定, および肺門リンパ節のmicroautoradiogramを作製, 解析した. 肺門集積は, 喫煙に有意な関係を認めたが, 年齢因子には有意な関係を認めなかった. 喫煙が肺門集積に関与している可能性がある. 喫煙負荷実験において肺門リンパ節の67Gaの集積が負荷群でコントロール群より有意に高く, その組織所見は, 類洞内のmacrophageの増生であった. これらのことより, 肺門集積部位は肺門リンパ節であり, 喫煙等の因子の影響でRES増生が盛んになり, 67Gaの集積をきたしたと推測される. 「I. 目的」67Ga-citrate(以下67Gaと略す)は, 腫瘍, 炎症以外にも唾液腺, 乳腺等の正常組織にも集積されることが多数報告されている. |
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| Practice | 臨床医学：一般 |
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| Keywords | 67Ga hilar accumulation, Smoking, Microautoradiogram, 67Ga scintigram, Quantitative analysis. |
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| English |
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| Title | Investigation of the Gallium-67 Citrate Hilar Accumulation - Especially the Relationship between the Hilar Accumulation and Smoking - |
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| Subtitle | Original Articles |
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| Authors | Yuji SUTO |
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| Authors(kana) | |
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| Organization | Department of Radiology, Tottori University School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 24 |
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| Number | 3 |
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| Page | 235-244 |
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| Year/Month | 1987/3 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary]To study the 67Ga hilar accumulation, author quantitatively analyzed 67Ga scintigrams of patients having no chest disease and normal chest roentgenograms. Relationship between hilar accumulation and smoking was quantitatively and experimentally studied. The conclusions were as follows: 1. There was significant relationship between smoking and 67Ga hilar accumulation but there was no significant relationship between aging and the hilar accumulation. 2. The 67Ga uptake of the hilar lymph node of smoked rat was higher than that of control group on microautoradiogram. The histological finding of the hilar lymph node of smoked rat was sinus histiocytosis. 3. Activated histiocytosis of hilar lymphatic sinus by some factors including smoking seemed to be responsible for 67Ga hilar accumulation, of which mechanism was unknown. |
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| Practice | Clinical medicine |
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| Keywords | 67Ga hilar accumulation, Smoking, Microautoradiogram, 67Ga scintigram, Quantitative analysis. |
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