Japanese
Title肥大心における左室拡張期動態
Subtitle原著
Authors池園徹*, 尾崎正治**, 山岸隆**, 清水達朗**, 古谷雄司**, 楠川禮造**
Authors(kana)
Organization*北九州市立戸畑病院内科, **山口大学医学部第二内科
Journal核医学
Volume24
Number2
Page157-164
Year/Month1987/2
Article原著
Publisher日本核医学会
Abstract「要旨」肥大心における左室拡張期動態の相違を検討するため, 高血圧性心肥大(HT)19例, 肥大型心筋症(HCM)11例, 健常者(N)13例を対象に心電図同期心プールシンチグラムを行い, 左室容量曲線およびその一次微分, 二次微分曲線の解析を行った. 収縮期特性では, 3群間に有意差はなかった. 拡張期特性では, 最大充満速度(PFR)は, HT群がHCM群に比べ, 有意(p<0.05)に低下したが, 拡張初期流入率(%EFV)は, 逆にHCM群がHT群より有意(p<0.01)に低下した. さらに, 最大充満加速度は, HCM群がHT群に比べ, 有意(p<0.001)に高値を示した. 以上の結果より, HT群は, 拡張初期より充満期に障害が強く, HCM群では, 充満期より拡張初期に障害がみられた. そして, HCM群では, 拡張初期の障害を加速度の増加をもって代償し, HT群では, 加速度の増加がないため充満期にも障害がみられることが示された.
Practice臨床医学：一般
KeywordsLeft ventricular hypertrophy, Left ventricular diastolic property, Peak filling rate, Early filling volume ratio, Peak filling acceleration.
English
TitleLeft Ventricular Diastolic Performance of Left Ventricular Hypertrophy
SubtitleOriginal Articles
AuthorsTohru IKEZONO*, Masaharu OZAKI**, Takashi YAMAGISHI**, Tatsuro SHIMIZU**, Yuji FURUTANI**, Reizo KUSUKAWA**
Authors(kana)
Organization*Department of Internal Medicine, Kitakyushu City Tobata Hospital, **The Second Division of Internal Medicine, Yamaguchi University School of Medicine
JournalThe Japanese Journal of nuclear medicine
Volume24
Number2
Page157-164
Year/Month1987/2
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary]To study left ventricular diastolic performance in different forms of left ventricular hypertrophy, ECG gated cardiac blood pool scan was performed in 11 patients with hypertrophic nonobstructive cardiomyopathy (HCM) and in 19 patients with hypertension (HT), and left ventricular volume curve (LVVC) was analyzed and compared with those of 13 normal subjects (N). Ejection fraction (EF) and early filling volume ratio (the ratio of volume increment of 100 msec later than the zero point in the first derivative of LVVC to the end diastolic volume) (%EFV) were computed from LVVC. Peak ejection rate (PER) and peak filling rate (PFR) were obtained from the first derivative of LVVC. Peak ejection acceleration (PEA) and peak filling acceleration (PFA) were calculated from the second derivative of LVVC. EF, PER and PEA did not show any difference between these 3 groups. PFR was lower in HT (2.6 +- 0.5) compared with those in HCM (3.0 +- 0.5) (p<0.05) and in N (3.4 +- 0.5) (p<0.001), but the %EFV in HCM (4.9 +- 1.8) was lower than those in HT (6.9 +- 1.9) (p<0.01) and in N (11.4 +- 1.4) (p<0.001). Moreover, PFA in HCM (27.9 +- 7.2) was increased than those in HT (20.2 +- 5.4) (p<0.01) with no differences between HCM and N (29.4 +- 8.1). Significant correlation was observed between PFR and PFA (Y=0.06X + 1.4. r=0.856. p<0.001). These result indicate that, in HCM, reduced increase in early left ventricular volume is compensated by a greater filling acceleration. In contrast, there is no compensation by filling acceleration in HT.
PracticeClinical medicine
KeywordsLeft ventricular hypertrophy, Left ventricular diastolic property, Peak filling rate, Early filling volume ratio, Peak filling acceleration.

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