| Japanese |
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| Title | 運動負荷201Tl心筋single photon emission CTの定量解析 : Bull's-eye法の虚血性心疾患評価における有用性 |
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| Subtitle | 原著 |
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| Authors | 成田充啓*, 栗原正*, 村野謙一*, 宇佐美暢久*, 本田稔**, 友延正弘**, 金尾啓右** |
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| Organization | *住友病院内科, **アイソトープ室 |
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| Journal | 核医学 |
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| Volume | 24 |
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| Number | 1 |
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| Page | 55-64 |
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| Year/Month | 1987/1 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」冠動脈疾患(CAD)の評価における201Tl心筋断層像(SPECT)の定量解析法であるBull's-eye法の有用性を健常17例, CAD 85例で検討した. 心筋SPECTは回転型ガンマカメラを用い, 運動負荷直後(EX)と負荷3時間後(RD)に撮影, 体軸横断断層像をもとに短軸断層像, 長軸矢状および水平断層像のoblique imageを作成した. EX, RDの短軸断層像をおのおの心尖部から心基部にむかい同心円状に配列, 各断層面での最大カウントcircumferential profile解析より心筋内Tl分布を極座標表示, また相対応する心筋でのTl washout(WO)rate(WO-Bull)も極座標表示し, 3つのfunctional mapを得た(Bull's-eye表示). WO rateの正常下限は健常例より求めた. CADの診断精度はoblique imageの視覚的判定にWO-Bullを併用することで向上, ことに3枝病変での正診率を27%から47%(p<0.05)に向上した. 本法は短時間で左室全域にわたるWO rateを計測しうると同時に, 灌流異常の部位, 広がりを左室全体との関連でとらえることを可能とし, CADの評価上有用である. |
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| Practice | 臨床医学：一般 |
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| Keywords | Myocardial SPECT, Bull's-eye map, Washout rate, Coronary artery disease. |
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| English |
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| Title | Quantitative Analysis of Exercise Stress Thallium-201 Myocardial Tomography : The Evaluation of Bull's-Eye Map Representation for the Detection of Coronary Artery Disease |
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| Subtitle | Original Articles |
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| Authors | Michihiro NARITA*, Tadashi KURIHARA*, Kenichi MURANO*, Masahisa USAMI*, Minoru HONDA**, Masahiro TOMONOBU**, Keisuke KANAO** |
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| Authors(kana) | |
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| Organization | *Department of Internal Medicine, **Division of Nuclear Medicine, Sumitomo Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 24 |
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| Number | 1 |
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| Page | 55-64 |
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| Year/Month | 1987/1 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary]To assess the ability of quantitative analysis of stress-redistribution Tl-201 rotational tomography to detect and localize coronary artery disease (CAD), we studied 17 normal subjects and 85 patients with CAD. Thirty-two projections were obtained over 180-degree by the rotating gamma camera both at immediately after exercise stress and 3 hours after exercise stress. After low-pass filtering, images were reconstructed into short-axis, horizontal long-axis and vertical long-axis tomograms. Both at exercise stress and redistribution, the maximum count circumferential profiles for each short-axis cuts were generated from apical to basal cut and they were expressed into two-dimensional polar functional maps (apex at the center) to represent myocardial Tl distribution. Similarly, myocardial Tl washout rates of the entire left ventricle were expressed as a two dimensional polar map. Normal limits of myocardial Tl washout rates were established from those of normal subjects. In cases with multivessel CAD, the use of Bull's-eye map, especially washout maps, made the detection of diseased coronary artery more accurate. And in patients with triple vessel disease (TVD), it improved the detection of TVD from 27% (visual inspection only) to 47% (p<0.05). In Bull's-eye map, as all tomographic data from the study can be displayed in functional maps (including washout rate), the extent and severity of myocardial ischemia can be detected easily and accurately. |
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| Practice | Clinical medicine |
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| Keywords | Myocardial SPECT, Bull's-eye map, Washout rate, Coronary artery disease. |
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