| Japanese |
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| Title | SPECTを用いた臓器容積および摂取率測定法の基礎的検討 |
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| Subtitle | 原著 |
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| Authors | 外山比南子*, 与那嶺茂道**, 山片敦**, 山田英夫**, 田中栄一***, 村田啓**** |
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| Authors(kana) | |
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| Organization | *筑波大学臨床医学系放射線科, **東京都老人医療センター核医学放射線部, ***放射線医学総合研究所物理部, ****虎の門病院放射線科 |
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| Journal | 核医学 |
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| Volume | 24 |
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| Number | 1 |
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| Page | 35-45 |
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| Year/Month | 1987/1 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」回転型ガンマ・カメラ等を使用したSPECTによる3次元画像診断は非侵襲的に行え, 臓器容積を定量できるうえに, 医薬品摂取率が測定できる. ここではファントム実験を行って, 生体内臓器の容積および医薬品摂取率測定法を検討した. 5種類の円筒ファントムに16通りの放射能分布を与えて, 正しい容積を与える最適いき値を等計数法で求めさらに放射能-計数較正曲線を算出した. 最適いき値はファントム容積が大きくなると下がり, バックグラウンドが高くなると上がる傾向にあった. 肝ファントム実験から, 形状によっても最適いき値が異なることが示唆された. 吸収補正法(RPC法, PRE法)によっても最適いき値は異なった. しかし, 一定の方法で較正することにより, 容積・放射能量ともに0.98以上のよい相関で算出できた. したがって, それぞれ類似の条件下で較正曲線を作成することにより本法の臨床応用が可能である. |
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| Practice | 臨床医学：一般 |
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| Keywords | Single photon emission CT, Organ volume, Uptake, Phantom study. |
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| English |
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| Title | Evaluation of Estimation Method for Organ Volume and Uptake with Single Photon Emission Computed Tomography (SPECT) |
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| Subtitle | Original Articles |
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| Authors | Hinako TOYAMA*, Shigemichi YONAMINE**, Atsushi YAMAGATA**, Hideo YAMADA**, Eiichi TANAKA***, Hajime MURATA**** |
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| Authors(kana) | |
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| Organization | *Institute of Clinical Medicine, University of Tsukuba, **Department of Nuclear Medicine and Radiological Science, Tokyo Metropolitan Geriatric Hospital, ***National Institute of Radiological Science, ****Division of Nuclear Medicine, Toranomon Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 24 |
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| Number | 1 |
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| Page | 35-45 |
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| Year/Month | 1987/1 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary]Estimation method for an organ volume and uptake was evaluated using five cylinder phantoms (113 cc-1,539 cc) and two liver phantoms with all purpose (AP) and high resolution (HR) collimators. The volume was calculated from the summation of voxels in the region districted by equi-count threshold level at each section of the SPECT image, which were reconstructed with two attenuation correction methods: radial post correction (RPC) by Tanaka and precorrection (PRE) by Sorenson. The optimum equi-count threshold level (percentage to maximum count), which gave the nearest volume to true phantom volume, was estimated for all phantom images and the activity-count calibration curve was also generated. The optimum threshold level is tending downward as increasing the volume. Higher back ground gave higher optimum equi-count threshold level. Further, the optimum equi-count threshold level is changed with a kind of collimator, form of the phantom and attenuation correction methods. Estimated volume and activity are well correlated (r>0.98) with their real values in the same situation. In RPC method than PRE method and in the estimation of activity than the estimation of volume, less dependence on the form of phantom was found from the present study comparing with cylinder and liver phantoms. In conclusion, the estimation for the volume and activity, furthermore uptake of pharmaceutical to the target organ with SPECT would be useful for clinical application, if the calibration study has done previously in the same situation as clinical one. |
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| Practice | Clinical medicine |
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| Keywords | Single photon emission CT, Organ volume, Uptake, Phantom study. |
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