| Japanese |
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| Title | m- [131I] iodobenzylguanidine (I-131 MIBG) シンチグラフィーの褐色細胞腫の診断における診断能 : コンピュータ断層撮影, 超音波断層撮影との比較 |
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| Subtitle | 原著 |
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| Authors | 酒井美知子*, 田所匡典**, 牧野直樹**, 石垣武男**, 安部哲太郎**, 佐久間貞行** |
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| Authors(kana) | |
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| Organization | *中部労災病院放射線科, **名古屋大学医学部放射線科 |
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| Journal | 核医学 |
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| Volume | 24 |
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| Number | 1 |
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| Page | 7-14 |
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| Year/Month | 1987/1 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」褐色細胞腫が疑われた28症例に30回のm-[131I]iodobenzylguanidine(I-131MIBG)シンチグラフィーを行った. そのうち確定診断の得られた24検査例についてI-131MIBGシンチグラフィーの意義と診断能についてコンピュータ断層撮影(CT), 超音波断層撮影(US)と比較し検討した. I-131MIBGのsensitivityは8/9(88.9%), specificityは15/15(100%), accuracyは23/24(95.8%)であった. 一方, CTのsensitivityは9/9(100%), specificityは10/15(66.7%), accuracyは19/24(79.2%)であり, USのsensitivityは8/9(88.9%), specificityは12/15(80.0%), accuracyは20/24(83.3%)であった. 褐色細胞腫の診断に際しI-131MIBGシンチグラフィーはCTに比べ腫瘍の大きさの面で限界があり, 今回の症例では検出限界は2.0×2.5×2.0cmであったが, CTやUSに比し, より特異性の高い検査法であることが示された. |
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| Practice | 臨床医学：一般 |
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| Keywords | Pheochromocytoma, Multiple endocrine neoplasia, I-131 MIBG, Computed tomography, Ultrasonography. |
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| English |
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| Title | Diagnostic Efficacy of m- [131I] Iodobenzylguanidine (I-131 MIBG) Scintigraphy in Locating Pheochromocytoma : Comparison with Computed Tomography and Ultrasonography |
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| Subtitle | Original Articles |
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| Authors | Michiko SAKAI*, Masanori TADOKORO**, Naoki MAKINO**, Takeo ISHIGAKI**, Tetsutaro ABE**, Sadayuki SAKUMA** |
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| Authors(kana) | |
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| Organization | *Department of Radiology, Chubu Rosai Hospital, **Department of Radiology, Nagoya University School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 24 |
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| Number | 1 |
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| Page | 7-14 |
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| Year/Month | 1987/1 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary]Scintigraphic images using I-131 MIBG were reviewed in the 28 patients with suspected pheochromocytoma. The diagnostic efficacy of the I-131 MIBG scintigraphy for location of mass was discussed comparing with computed tomography (CT) and ultrasonography (US). The smallest size of the pheochromocytoma revealed by both I-131 MIBG scintigraphy and US was 2.0 × 2.5 × 2.0 cm. On the other hand, CT detected smaller mass, 1.0 × 1.5 × 0.4 cm in size. The sensitivity was 88.9% in I-131 MIBG scintigraphy, 100% in CT, and 88.9% in US. The specificity was 100% in I-131 MIBG, 66.7% in CT, and 80.0% in US. And the accuracy was 95.8% in I-131 MIBG, 79.2% in CT, and 83.3% in US. Thus I-131 MIBG scintigraphy was proved to be more sensitive than both CT and US for the location of pheochromocytoma, and is an available method for the first choice. |
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| Practice | Clinical medicine |
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| Keywords | Pheochromocytoma, Multiple endocrine neoplasia, I-131 MIBG, Computed tomography, Ultrasonography. |
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