| Japanese |
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| Title | 心プール法による左室圧-容積曲線の検討 - 方法論を中心にして - |
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| Subtitle | 研究速報 |
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| Authors | 廣江道昭*, 杉本圭市**, 白井隆則**, 小池朗**, 丹羽明博**, 村松靖次**, 横田純一**, 谷口興一***, 太田淑子*, 日下部きよ子*, 松井進****, 熊野信雄****, 水川勝海***** |
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| Authors(kana) | |
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| Organization | *東京女子医科大学放射線医学教室核医学部, **北信総合病院内科, 放射線科, ***東京医科歯科大学医学部第二内科教室, ****東芝那須工場, *****東芝メディカル |
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| Journal | 核医学 |
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| Volume | 23 |
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| Number | 12 |
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| Page | 1749-1753 |
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| Year/Month | 1986/12 |
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| Article | 報告 |
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| Publisher | 日本核医学会 |
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| Abstract | 「I. はじめに」心機能解析には心内圧と心容積を同時に評価することが重要であり, 左室圧-容積曲線(以下P-V曲線)の作成が望まれている. 一般的な画像診断には造影剤を使用した左室造影法が汎用されている. しかし局所壁運動障害を示す症例では左室容積の計測上geometryに問題があり, またペーシング負荷や薬剤負荷による心機能動態を評価する際には数回に及ぶ造影は不可能である. 心エコー図を用いた研究もあるが, geometryによる影響はさらに強く, 心容積算定には問題がある. 心電図同期型心プール法は前述した諸問題に拘束されず, 心容積曲線を詳細に解析するには最適である. 著者らは心プール法と左室カテーテル法を同時に組合わせてP-V曲線を作成し, 左室機能の解析について基礎的臨床成績を得たので報告する. 「II. 対象と方法」「1. 対象」虚血性心疾患4例と心臓神経症2例の合計6例を選択し, 年齢は平均57±6歳であった. 全例に心臓カテーテル法がなされ診断された. |
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| Practice | 臨床医学：一般 |
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| Keywords | Pressure-volume loops, Gated radionuclide ventriculography, Micromanometer pressure, Atrial pacing. |
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| English |
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| Title | A New Method for a Left Ventricular Pressure-volume Loop Using Gated Radionuclide Ventriculography and Simultaneous Micromanometer Pressure Measurements in Human Beings |
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| Authors | Michiaki HIROE*, Keiichi SUGIMOTO**, Takanori SHIRAI**, Akira KOIKE**, Akihiro NIWA**, Yasuji MURAMATSU**, Junichi YOKOTA**, Koichi TANIGUCHI***, Yoshiko OHTA*, Kiyoko KUSAKABE*, Susumu MATSUI****, Nobuo KUMANO****, Katsumi MIZUKAWA***** |
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| Authors(kana) | |
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| Organization | *Department of Radiology, Tokyo Women's Medical College, **Medicine and Radiology, Hokushin Sogo Hospital, ***Department of Second Medicine, Tokyo Medical and Dental University, ****Toshiba Nasu Industry, *****Toshiba Medical |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 23 |
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| Number | 12 |
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| Page | 1749-1753 |
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| Year/Month | 1986/12 |
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| Article | Report |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary]A new method for a left ventricular pressure-volume (P-V) loop was created to assess the P-V relations in response to heart rate by atrial pacing in 6 patients. Absolute left ventricular volume was measured using gated radionuclide ventriculography and cardiac output by Swan-Ganz catheter, and pressure recordings were simultaneously done by micromanometer catheter. Ventricular volume and pressure measurements were ploted from the synchronized R-wave into 32 points throughout a cardiac cycle. Then sequential P-V loops were drawn during atrial pacing tachycardia. The loops shifted to leftward in response to pacing tachycardia in 4 patients without pacing-induced ischemia. However, in 2 patients with ischemia, the loops shifted to upward with an elevation of left ventricular end-diastolic pressure and a reduction of ejection fraction. This study indicates that P-V relations could be analyzed by this method using radionuclide volume and simultaneous pressure measurements, and that sequential P-V loop may be useful for evaluating left ventricular performance and contractility state under various interventions. |
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| Practice | Clinical medicine |
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| Keywords | Pressure-volume loops, Gated radionuclide ventriculography, Micromanometer pressure, Atrial pacing. |
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