| Japanese |
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| Title | 全身用リング型SPECT装置を用いたTl-201心筋ダイナミックスキャン |
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| Subtitle | 《原著》 |
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| Authors | 小出治敏*, 米倉義晴*, 藤田透*, 鳥塚莞爾*, 野原隆司**, 不藤哲郎**, 神原啓文**, 河合忠一**, 小西裕***, 伴敏彦*** |
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| Authors(kana) | |
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| Organization | *京都大学医学部附属病院放射線核医学科, **第三内科, ***心臓血管外科 |
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| Journal | 核医学 |
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| Volume | 23 |
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| Number | 11 |
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| Page | 1523-1531 |
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| Year/Month | 1986/11 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」: 心筋のTl-201分布の経時的変化を調べる目的で, 全身用リング型多層SPECT装置を用いて, 虚血性心疾患を対象に運動負荷後ダイナミックSPECTスキャンを行った. 冠動脈造影で異常が見られなかった症例では静注後30分以内の早期からほぼ一定の速さでTl-201のwashoutが始まっており, また虚血心筋では正常例とは異なる種々の経時的変化が認められ, 心筋血流の状態を反映するものと考えられた. 心筋虚血の診断に早期のwashoutは重要な意義を有すると考えられる. |
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| Practice | 臨床医学：一般 |
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| Keywords | Single photon emission computed tomography, Dynamic scan, Tl-201, Ischemic heart disease. |
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| English |
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| Title | Dynamic Single Photon Emission Computed Tomography of Tl-201 with Exercise Loading |
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| Subtitle | Original Articles |
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| Authors | Harutoshi KOIDE, Yoshiharu YONEKURA, Tohru FUJITA, Kanji TORIZUKA, Ryuji NOHARA, Tetsuo FUDO, Hirofumi KAMBARA, Chuichi KAWAI, Yutaka KONISHI, Toshihiko BAN |
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| Authors(kana) | |
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| Organization | Kyoto University School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 23 |
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| Number | 11 |
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| Page | 1523-1531 |
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| Year/Month | 1986/11 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] : Single photon emission computed tomography (SPECT) with Tl-201 has been reported to provide accurate means for diagnosis of coronary artery disease (CAD) . The purpose of this study is to examine the serial changes in regional myocardial activity of Tl-201 injected during exercise loading in CAD using a multidetector SPECT system. Four cases without coronary stenosis (N) and 17 patients with CAD including 9 cases with prior myocardial infarction (MI) were studied. TI-201 was injected during submaximal exercise loading with a bicycle ergometer. Serial dynamic SPECT scan was performed every 5 min until 30 min after injection, followed by additional 3 scans for 10 min at 1 hr, 2 hr and 3 hr after injection. These SPECT images were corrected for the acquisition time, but no corrections were made for photon attenuation and scattering. N revealed uniform distribution throughout the study, and rapid washout was observed from the early period in 3/4 cases (10 to 24% for initial 25 min) . CAD showed various patterns of abnormal distribution and washout. In addition, the changes in regional distribution of Tl-201 were observed during the early period. These preliminary results indicate the significance of the early washout during the 30 min after injection of Tl-201, and careful consideration should be taken in calculating the washout rate by a conventional SPECT system with a rotating gamma camera. |
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| Practice | Clinical medicine |
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| Keywords | Single photon emission computed tomography, Dynamic scan, Tl-201, Ischemic heart disease. |
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