| Japanese |
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| Title | 99mTc-rhenium-colloidと67Ga-citrateを用いての2核種同時シンチグラフィー (1) - 基礎的研究と悪性リンパ腫における臨床的有用性について - |
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| Subtitle | 《原著》 |
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| Authors | 丸尾直幸*, 中坊俊雅*, 小沢勝*, 小林裕*, 近藤元治*, 岡本邦雄**, 山下正人**, 三木昌宏*** |
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| Authors(kana) | |
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| Organization | *京都府立医科大学第一内科, **放射線科, ***京都大学医学部第一内科 |
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| Journal | 核医学 |
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| Volume | 23 |
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| Number | 8 |
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| Page | 1009-1018 |
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| Year/Month | 1986/8 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」: 99mTc-rhenium-colloidリンパ節シンチグラフィーと67Ga-citrate腫瘍シンチグラフィーの同時撮像について基礎的に検討するとともに, 悪性リンパ腫に応用した. 99mTcは140keVに, また67Gaは93keV, 184keV, 296keVにエネルギーピークを示した. 撮像に際して, 両シンチ像上での病変部の相互位置関係を正しく比較対応させるために同一の中エネルギーコリメータを用いた. そしてエネルギーピークの差を利用し, 2核種の各放射活性を分離し像を得るために, 67Gaのwindowには184keV±20%と296keV±20%を, 99mTcには140keV±10%を用いた. 67Ga windowでは99mTcの影響は, 99mTc windowの測定値の0.2%ときわめて低かったが, 99mTc windowでの67Gaの影響は, 67Ga windowの測定値の23.7%であった. しかし正常および悪性リンパ腫例で99mTc windowのシンチ像が, 67Gaの影響で読影困難になることはなかった. この2核種同時シンチグラフィーは, 67Ga window像で悪性リンパ腫11例中9例にradioactivity集積の陽性像を, また99mTc window像で欠損所見の陰性像を示した. この陽性像と陰性像とを相補的に診断することにより, 両方のシンチグラフィーを単独に用いた場合の読影上の欠点を補うことが可能となり, 臨床的に有用性が高いと考えられる. |
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| Practice | 臨床医学：一般 |
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| Keywords | 99mTc-rhenium-colloid, 67Ga-citrate, Energy spectra, Dual tracer scintigraphy, Malignant lymphoma. |
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| English |
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| Title | Dual Tracer Scintigraphy Using 99mTC-rhenium-Colloid and 67Ga-citrate (1) : A Basic Investigation and Clinical Evaluation |
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| Subtitle | Original Articles |
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| Authors | Naoyuki MARUO*, Toshimasa NAKABO*, Masaru OZAWA*, Yutaka KOBAYASHI*, Motoharu KONDO*, Kunio OKAMOTO**, Masato YAMASHITA**, Masahiro MIKI*** |
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| Authors(kana) | |
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| Organization | *First Department of Internal Medicine, Kyoto Prefectural University of Medicine, **Department of Radiology, Kyoto Prefectural University of Medicine, ***First Department of Internal Medicine, Faculty of Medicine, Kyoto University |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 23 |
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| Number | 8 |
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| Page | 1009-1018 |
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| Year/Month | 1986/8 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] : Scintigraphy using 99mTc-rhenium-colloid and 67Ga-citrate was basically investigated and performed in 8 patients with malignant lymphoma. The energy spectrum of 99mTc showed a different peak from that of 67Ga did. Therefore, the radioactivity of 99mTc and 67Ga was measured simultaneously with the same collimeter to clarify the relationship of the locations of lesions in both scintigrams. The windows used for the 67Ga were 184KeV+-20% and 296 KeV+-20%, and that for the 99mTc was 140 KeV+-10%. The percentage of 67Ga radioactivity to the whole radioactivity measured using the 99mTc window was 23.7% of the radioactivity measured using the 67Ga windows. However, the image obtained with the 99mTc window was not substantially influenced by the 67Ga radioactivity. In contrast, the influence of 99mTc on the activity measured using the 67Ga window was negligible. This dual tracer scintigraphy using two different radioactive isotopes, 67Ga-citrate and 99mTc-rhenium-colloid, gave positive and negative findings respectively in the neoplastic regions. This finding suggests that this dual tracer scintigraphy is more valuable than scintigraphy using 99mTc-rhenium-colloid or 67Ga-citrate. |
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| Practice | Clinical medicine |
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| Keywords | 99mTc-rhenium-colloid, 67Ga-citrate, Energy spectra, Dual tracer scintigraphy, Malignant lymphoma. |
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