| Japanese |
| Title | 多発性骨髄腫の骨病変の評価における骨・骨髄シンチグラフィの有用性 |
| Subtitle | 《原著》 |
| Authors | 大塚信昭*, 福永仁夫*, 曽根照喜*, 永井清久*, 柳元真一*, 友光達志*, 小野志磨人*, 村中明*, 井上信正**, 杉原尚**, 八幡義人**, 森田陸司* |
| Authors(kana) | |
| Organization | *川崎医科大学核医学科, **血液内科 |
| Journal | 核医学 |
| Volume | 23 |
| Number | 8 |
| Page | 999-1007 |
| Year/Month | 1986/8 |
| Article | 原著 |
| Publisher | 日本核医学会 |
| Abstract | 「要旨」: 多発性骨髄腫15例 (未治療例7例, 化学療法施行例8例) について, 骨・骨髄シンチグラフィを施行し, 多発性骨髄腫の骨病変の検出における有用性を検討した. 多発性骨髄腫の未治療例7例の骨シンチグラフィの内訳は正常像3例および欠損像4例であった. これらの症例では骨髄シンチグラフィの方がより多くの病変部位を指摘でき, また浸潤範囲を明瞭に描出できた. 一方, 化学療法施行例の8例は骨シンチグラム上, 全例, 集積増加を示した. 一方, 骨髄シンチグラフィでは骨シンチ上, 集積増加を示した部位でも正常像を呈する例が多く認められた. 多発性骨髄腫の骨X線像は特徴的な所見を示すが, 治療による骨病変の変化はとらえ難い. したがって, 多発性骨髄腫の骨病変の評価には骨シンチグラフィに骨髄シンチグラフィを併用することの有用性が認められた. |
| Practice | 臨床医学:一般 |
| Keywords | Multiple myeloma, Bone-marrow scintigraphy, Bone scintigraphy. |
| English |
| Title | The Usefulness of Bone and Bone-marrow Scintigraphy in the Detection of Bone Lesion in Patients with Multiple Myeloma |
| Subtitle | Original Articles |
| Authors | Nobuaki OTSUKA, Masao FUKUNAGA, Teruki SONE, Kiyohisa NAGAI, Shinichi YANAGIMOTO, Tatsushi TOMOMITSU, Shimato ONO, Akira MURANAKA, Nobumasa INOUE, Takashi SUGIHARA, Yoshihito YAWATA, Rikushi MORITA |
| Authors(kana) | |
| Organization | Kawasaki Medical School |
| Journal | The Japanese Journal of nuclear medicine |
| Volume | 23 |
| Number | 8 |
| Page | 999-1007 |
| Year/Month | 1986/8 |
| Article | Original article |
| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
| Abstract | [Summary] : We used a combination of bone and bone marrow scintigraphy to study 15 patients with multiple myeloma (7 in untreated group and 8 in chemotherapy group) . Of the 3 cases in untreated group whose 99mTc-methylene diphosphonate (MDP) bone scans showed no abnormality, one had abnormal bone-marrow scintigraphy. In other 4 cases of untreated group whose 99mTc-MDP bone scan showed cold defects, 99mTc-sulfur colloid bone-marrow scintigraphy clearly delineated the areas of tumor-cell invasion. In all chemotherapy cases, multiple hot spots were observed on bone scintigram, but abnormalities were not recognized on bone-marrow scintigram in all of their lesions. In conclusion, the combination technique of bone and bone-marrow scintigraphy was a useful method in evaluating bone lesions in patients with multiple myeloma. |
| Practice | Clinical medicine |
| Keywords | Multiple myeloma, Bone-marrow scintigraphy, Bone scintigraphy. |