Japanese
Title運動負荷201Tl心筋SPECTによる拡張型心筋症の検討 - 第1報 虚血性心疾患との対比および左室造影所見との関連 -
Subtitle《原著》
Authors中野赳*, 二神康夫*, 矢田隆志*, 山室匡史*, 小西得司*, 竹沢英郎*, 伊藤綱朗**, 前田寿登**, 中川毅**
Authors(kana)
Organization*三重大学医学部第一内科, **放射線科
Journal核医学
Volume23
Number7
Page887-897
Year/Month1986/7
Article原著
Publisher日本核医学会
Abstract「要旨」: 拡張型心筋症 (DCM) の非観血的診断, 病態解明のためDCM 20例, 拡張終期容量200ml以上の陳旧性心筋梗塞20例 (OMI) に運動負荷201Tl心筋SPECTを施行した. (1) 左室拡大は全例, 負荷像における集積異常はDCM 85%, OMI 100%に認められた. (2) 負荷像における集積異常はDCMでは2セグメント以下が多く, 完全欠損が少なく, abnormal perfusion score (APS) は6以下 (18/20 : 90%) が多かった. 一方, OMIでは全例APS 7以上であった. (3) 壁運動異常と集積異常との対比ではOMIでは良好な相関が認められたが, DCMでは認められなかった. (4) 再分布はDCM 3例, OMI 9例に認められたが, OMIの2例を除き軽度であった.以上より運動負荷201Tl心筋SPECTはDCMの非観血的診断, 特に虚血性心疾患の除外に有用であり, また高度壁運動部位が必ずしも高度集積異常を示すとは限らなかった.
Practice臨床医学:一般
KeywordsDilated cardiomyopathy, Old myocardial infarction, Stress 201Tl myocardial SPECT, Left ventriculography.
English
TitleEvaluation of Dilated Cardiomyopathy by Stress Tl-201 Myocardial Single Photon Emission Computed Tomography (SPECT) - Comparison with Old Myocardial Infarction with Dilated Left Ventricle and Relationship between SPECT Finding and Left Ventriculographic Finding -
SubtitleOriginal Articles
AuthorsTakeshi NAKANO*, Yasuo FUTAGAMI*, Takashi YADA*, Masashi YAMAMURO*, Tokuji KONISHI*, Hideo TAKEZAWA*, Tsunao ITO**, Hisato MAEDA**, Tsuyoshi NAKAGAWA**
Authors(kana)
Organization*The First Department of Internal Medicine, **Department of Radiology, Fuculty of Medicine, Mie University
JournalThe Japanese Journal of nuclear medicine
Volume23
Number7
Page887-897
Year/Month1986/7
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] : Stress Tl-201 myocardial SPECT was performed in 20 dilated cardiomyopathy (DCM) and 23 old myocardial infarction (OMI : ED volume>=200 ml by left ventriculography=LVG) for non-invasive diagnosis of DCM. We assessed the perfusion abnormality of 5 segments (anterior-anterolateral, septal, apical, posterolateral, postero-inferior) in SPECT images in grades as follows ; 0 : normal, 1 : mild low uptake, 2 : severe low uptake, 3 : complete defect. Thus, we defined the abnormal perfusion score (APS) as the summation of the grades in 5 segments. 1) Perfusion abnormality was found 85% in DCM and 100% in OMI by stress SPECT images. 2) Rare complete defect, abnormal perfusion segments under 3 and APS under 7 were characteristic findings in DCM, and could finally distinguish DCM from OMI with the finding of APS under 7 (18/20 : 90%) in stress images. 3) The perfusion abnormality in delayed images had a good relation with wall motion abnormality in OMI, but not DCM. 4) Redistribution was found only 3 cases with DCM (15%) and 9 cases with OMI (39%) , but mild without 2 cases with OMI. 5) Inspite of exercise induced severe symptom and arrhythmia in some DCM cases, stress SPECT was efficient especially to rule out ischemic heart disease. Thus, we conclude that stress Tl-201 myocardial SPECT is useful method for the non-invasive differential diagnosis of DCM from ischemic heart disease, but wall motion abnormality has no good relation with perfusion abnormality.
PracticeClinical medicine
KeywordsDilated cardiomyopathy, Old myocardial infarction, Stress 201Tl myocardial SPECT, Left ventriculography.

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