Japanese
Title高カルシウム血症を合併した悪性腫瘍の骨シンチグラフィ
Subtitle短報
Authors福永仁夫*, 大塚信昭*, 曾根照喜*, 永井清久*, 小野志磨人*, 村中明*, 古川高子*, 柳元真一*, 友光達志*, 森田陸司*
Authors(kana)
Organization*川崎医科大学核医学科
Journal核医学
Volume23
Number5
Page495-498
Year/Month1986/5
Article報告
Publisher日本核医学会
Abstract「I. 緒言」進行した末期の悪性腫瘍では, 高カルシウム (Ca) 血症の合併はまれではない. この高Ca血症を合併する悪性腫瘍 (malignancy associated with hypercalcemia, MAH) の病因は, 主として骨吸収の亢進による骨からのCa塩の溶出に基づくと考えられる. そこで, MAH症例に骨シンチグラフィを施行し, 骨集積パターンを観察するとともに, 高Ca血症発現における骨病態を検討した. 「II. 対象と方法」昭和59年9月から昭和60年8月までの1年間に本院核医学科で骨シンチグラフィを施行し, 同時に高Ca血症を呈した悪性腫瘍の17例を対象とした. その内訳は, 乳癌4例, 肺癌3例, 喉頭癌2例, 下顎癌, 扁桃癌, 胆のう癌, 肝癌, 胃癌, 骨髄腫, 前立腺癌と腎盂癌の重複癌, 前立腺癌と喉頭癌の重複癌のそれぞれ1例であった.
Practice臨床医学:一般
KeywordsBone scintigraphy, Hypercalcemia, Malignancy, Bone metastasis, Humoral hypercalcemia
English
TitleBone Scintigraphy in Patients with Malignancy Associated with Hypercalcemia
SubtitleShort Communications
AuthorsMasao FUKUNAGA, Nobuaki OTSUKA, Teruki SONE, Kiyohisa NAGAI, Shimato ONO, Akira MURANAKA, Takako FURUKAWA, Shinichi YANAGIMOTO, Tatsushi TOMOMITSU, Rikushi MORITA
Authors(kana)
OrganizationDepartment of Nuclear Medicine, Kawasaki Medical School
JournalThe Japanese Journal of nuclear medicine
Volume23
Number5
Page495-498
Year/Month1986/5
ArticleReport
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] In 17 patients with malignancy associated with hypercalcemia (MAH), showing more than 1.30 mmol/L of ionized calcium concentration, bone scintigraphy using 99mTc-MDP was performed to evaluate the bone lesions. Whole body scintigrams were classified into 3 groups, (1) multiple hot spots, (2) diffusely increased uptake of radioactivity on spine, and (3) normal bone imaging, and the results were studied. Findings of multiple hot spots, indicating bone metastasis, were observed on 5 cases. In the remaining 12 cases, no focal abnormalities of radioactive accumulation were recognized, and, except 1 case with multiple myeloma, the possibility of so-called humoral hypercalcemia on bone scintigram might be suggested. It was shown that bone scintigraphy in MAH was interesting and useful method in clarifying the pathogenesis of hypercalcemia.
PracticeClinical medicine
KeywordsBone scintigraphy, Hypercalcemia, Malignancy, Bone metastasis, Humoral hypercalcemia

【全文PDF】