| Japanese |
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| Title | 肥大型心筋症の運動負荷心筋シンチにおけるWashout Rateの検討 |
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| Subtitle | 短報 |
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| Authors | 津田隆志*, 閏間美智子*, 古寺邦夫*, 小島研司*, 渡辺賢一*, 相沢義房*, 荒井裕*, 柴田昭*, 木村元政**, 小田野幾雄**, 酒井邦夫**, 浜斎***, 三谷亨*** |
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| Authors(kana) | |
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| Organization | *新潟大学医学部第一内科, **放射線科, ***木戸病院RI室 |
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| Journal | 核医学 |
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| Volume | 23 |
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| Number | 5 |
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| Page | 489-494 |
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| Year/Month | 1986/5 |
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| Article | 報告 |
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| Publisher | 日本核医学会 |
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| Abstract | 「I. はじめに」肥大型心筋症 (HCM) においても, 冠動脈疾患 (CAD) と同様に, 運動負荷心筋シンチグラムにおいて, 灌流低下, 再分布を示すことが報告されている. 今回, われわれはCADにおいて心筋虚血の定量的指標として用いられているWashout Rate (WR) を, HCM例でも求め, その意義について, 再分布や臨床指標との関係より検討したので報告する. 「II. 対象」対象は, 正常例12例, HCM 18例で, 平均年齢は, おのおの48±8歳 (Mean±SD), 44±10歳であった. HCMの診断は, 厚生省特定疾患特発性心筋症調査研究班の「診断の手引き」に従い, 肥大型閉塞性心筋症 (HOCM) 6例, 肥大型非閉塞性心筋症 (HNCM) 9例, 心尖部肥大型心筋症 (APH) 3例の三型に分けて検討した. 「III. 方法」1) 運動負荷心筋シンチグラムでは, エルゴメーターによる多段階負荷法 (25Wより3分間隔で, 25Wずつ増量) を行った. |
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| Practice | 臨床医学：一般 |
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| Keywords | Hypertrophic cardiomyopathy, Exercise myocardial scintigraphy, Washout rate, Redistribution |
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| English |
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| Title | Study of Washout Rate (WR) in Hypertrophic Cardiomyopathy (HCM) by Exercise Myocardial Scintigraphy (EMS) |
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| Subtitle | Short Communications |
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| Authors | Takashi TSUDA*, Michiko URUMA*, Kunio KODERA*, Kenji OJIMA*, Kenichi WATANABE*, Yoshifusa AIZAWA*, Yutaka ARAI*, Akira SHIBATA*, Motomasa KIMURA**, Ikuo ODANO**, Kunio SAKAI**, Hitoshi HAMA***, Tohru MITANI*** |
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| Authors(kana) | |
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| Organization | *The First Department of Internal Medicine, **Department of Radiology, Niigata University School of Medicine, ***Kido Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 23 |
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| Number | 5 |
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| Page | 489-494 |
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| Year/Month | 1986/5 |
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| Article | Report |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Reduced coronary reserve in HCM is reported. Recently, the defect and redistribution in HCM by EMS is showed as same as coronary artery disease (CAD). In this study, we assessed WR in HCM that was used in diagnosis of CAD and relationship between WR and redistribution. Twelve normal persons and eighteen patients in HCM were compared. WR by EMS in HCM was calculated in 45 degree LAO view and was estimated for three segments (anteroseptal, inferior and lateral segment). The end point of exercise was symptom-limited. Reduced WR was below the normal limits (mean - 2 SD). Reduced WR was showed in 16 segments of 7 patients (39%) and in 6 segments of 4 patients in accordance with redistribution. Max heart rate at end point in HCM was lower than normal and that in HCM with reduced WR was lower than normal WR. These results suggest that the reduced WR in HCM may be caused by the regional ischemia and the effect of exercise workloads must be considered. |
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| Practice | Clinical medicine |
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| Keywords | Hypertrophic cardiomyopathy, Exercise myocardial scintigraphy, Washout rate, Redistribution |
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