| Japanese |
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| Title | 99mTc-DTPA短時間2回投与法による運動負荷レノグラム - deconvolution analysisによる本態性高血圧症の検討 - |
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| Subtitle | 短報 |
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| Authors | 窪田靖志*, 宮尾賢爾*, 嶺尾徹*, 岡嶋泰*, 楠岡茂宏*, 村田稔**, 小寺秀幸**, 山田親久**, 杉原洋樹***, 足立晴彦***, 山下正人****, 細羽実***** |
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| Authors(kana) | |
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| Organization | *京都第二赤十字病院内科, **放射線科, ***京都府立医科大学第二内科, ****放射線科, *****島津製作所 |
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| Journal | 核医学 |
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| Volume | 23 |
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| Number | 3 |
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| Page | 267-271 |
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| Year/Month | 1986/3 |
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| Article | 報告 |
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| Publisher | 日本核医学会 |
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| Abstract | 「I. はじめに」従来より使用されている腎機能評価法としてのレノグラフィは安静状態に行われる. 最近, 運動負荷や薬物負荷の施行についての報告がされているものの十分に検討されていないのが現状である. 著者らは, 99mTc-DTPAを短時間に2回投与し, Matrix法によるdeconvolution analysisを用いてGFRの指標となるH0を求め, 本態性高血圧者の運動負荷時の腎機能を検討したので報告する. 「II. 対象と方法」「A. 安静時2回投与法による再現性の検討」正常者および腎機能障害者, 計13名を対象とした. 方法は, 被検者に200mlの飲水をさせた後シンチレーションカメラ(シーメンス社製ZLC/75)を背部に設定し, 2mCiの99mTc-DTPAを肘静脈より急速静注し直ちに10mlの生食でフラッシュした. 島津社製シンチパック1200を使用して64×64matrix sizeで20sec/frameのimage modeで20分間のdata採取を行った. |
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| Practice | 臨床医学：一般 |
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| Keywords | Exercise renography, 99mTc-DTPA, Deconvolution analysis, Two-times injection method, Essential hypertension. |
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| English |
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| Title | Exercise Renography with Two-times Injection of 99mTc-DTPA at a Short Interval - Deconvolution Analysis in Normal Subjects and Patients with Essential Hypertension - |
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| Subtitle | Short Communication |
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| Authors | Yasushi KUBOTA*, Kenji MIYAO*, Thoru MINEO*, Yasushi OKAJIMA*, Sigehiro KUSUOKA*, Minoru MURATA**, Hideyuki KOTERA**, Chikahisa YAMADA**, Hiroki SUGIHARA***, Haruhiko ADACHI***, Masato YAMASHITA****, Minoru HOSOBA***** |
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| Authors(kana) | |
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| Organization | *Department of Internal Medicine, **Department of Radiology, Kyoto Second Red Cross Hospital, ***Department of Second Internal Medicine, ****Department of Radiology, Kyoto Prefectural University of Medicine, *****Shimadzu Corporation |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 23 |
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| Number | 3 |
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| Page | 267-271 |
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| Year/Month | 1986/3 |
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| Article | Report |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | We deviced a concise method of renographies with two-times injection of 99mTc-DTPA at a short interval. The renographic data were analized by deconvolution method, and H0 values, an index of renal function, was calculated. A first renography was performed at resting state, and at approximately 30 min after it a second study was performed either at resting stage (n=13) or during exercise given by upright ergometer(n=18). There is a good correlation (R=0.97) between the two H0 values in the same patients (n=13) at resting state. This may prove the validity of this method. H0 values in exercise were decreased both in normal subjects (n=9) and in hypertensive patients (n=9). The rate of changes in H0 values was significantly larger in hypertensive patients (p<0.01) than in normal subjects. These results may indicate that the renal circulation was impared in hypertension. And this two-times injection method of renography is useful in evaluating renal circulation on various conditions. |
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| Practice | Clinical medicine |
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| Keywords | Exercise renography, 99mTc-DTPA, Deconvolution analysis, Two-times injection method, Essential hypertension. |
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