| Japanese |
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| Title | 各種疾患における脾収縮能について |
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| Subtitle | 原著 |
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| Authors | 飯尾篤*, 村瀬研也**, 伊東久雄**, 渡辺祐司**, 河村正*, 浜本研** |
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| Authors(kana) | |
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| Organization | *愛媛大学医学部附属病院中央放射線部, **放射線科 |
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| Journal | 核医学 |
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| Volume | 23 |
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| Number | 3 |
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| Page | 259-266 |
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| Year/Month | 1986/3 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」各種疾患患者45例について, single photon emission computed tomography(SPECT)を用いてepinephrineによる脾収縮能を検討した. 対照とした5例の収縮率および脾内カウントの減少率は, おのおの34.5±10.0%および16.4±6.9%であった. 脾浸潤ありと診断したnon-Hodgkin lymphomaでは収縮率およびカウントの減少率の平均は, 12.8±5.8%(6例)および2.5±1.6%(5例)であって, 脾浸潤なしと考えられたnon-Hodgkin lymphomaの平均値27.3±7.0%(8例)および9.4±7.0%(7例)に比べ両値とも低値であり, 前者は危険率1%以下で有意であった. 門脈うっ血性脾種7例の両値の平均は, 33.5±6.7%および13.8±4.5%と対照に比べ有意差は認められなかった. 脾腫を伴った白血病3例では全例収縮率およびカウントの減少率の著しい低下が認められた. また特発性血小板減少性紫斑病および原発巣不明の脾転移各1例においても両値の著明な低下が認められた. |
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| Practice | 臨床医学：一般 |
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| Keywords | Splenic diseases, SPECT, Radionuclide study, Epinephrine, Malignant lymphoma. |
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| English |
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| Title | Splenic Contraction in Patients with Various Disorders |
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| Subtitle | Original Articles |
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| Authors | Atsushi IIO*, Kenya MURASE**, Hisao ITO**, Yuji WATANABE**, Masashi KAWAMURA*, Ken HAMAMOTO** |
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| Authors(kana) | |
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| Organization | *Division of Central Radiology, Ehime University Hospital, **Department of Radiology, Faculty of Medicine, Ehime University |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 23 |
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| Number | 3 |
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| Page | 259-266 |
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| Year/Month | 1986/3 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | To investigate the pathophysiology of human spleen, splenic contraction following subcutaneous injection of epinephrine was measured in 45 patients with various disorders using single photon emission computed tomography (SPECT). The splenic contraction rates and percent decreases in splenic counts (ejection rates) in 5 controls were 34.5+-10.0 percent (mean+-SD) and 16.4+-6.9 percent respectively. With regard to non-Hodgkin lymphoma, the splenic contraction and ejection rates in 8 patients with no splenic involvement diagnosed by CT and/or 67Ga scintigraphy were 27.3+-7.0 percent and 9.4+-7.0 percent respectively, while these values in 6 patients with splenic involvement diagnosed by presence of splenomegaly, CT and/or 67Ga scintigraphy were 12.8+-5.8 percent and 2.5+-1.6 percent respectively. Both the values in the patients with splenic involvement were low (p<0.01, p<0.1) compared with those in the patients without splenic involvement. The splenic contraction and ejection rates in 7 patients with splenomegaly due to portal hypertension were averaged 33.5+-6.7 percent and 13.8+-4.5 percent respectively. These values were comparable to those in controls. All 3 patients with leukemia and splenomegaly showed exceedingly low values of the splenic contraction and ejection rates. The values were also remarkably low in a patient with splenic metastasis of unknown origin. |
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| Practice | Clinical medicine |
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| Keywords | Splenic diseases, SPECT, Radionuclide study, Epinephrine, Malignant lymphoma. |
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