Japanese
Title201Tl心筋ECTによる冠状動脈狭窄病変の定量的評価 - washout rateを併用したcircumferential profile法による評価 -
Subtitle原著
Authors伊藤綱朗*, 竹田寛*, 前田寿登*, 中川毅*, 山口信夫*, 牧野克俊**, 二神康夫**, 小西得司**
Authors(kana)
Organization*三重大学医学部放射線科, **第一内科
Journal核医学
Volume23
Number1
Page43-53
Year/Month1986/1
Article原著
Publisher日本核医学会
Abstract「要旨」冠状動脈造影と左室造影の行われた71例を対象に, 運動負荷時および再分布時の201Tl心筋ECTを施行し, 各心筋断層像における201Tlの分布およびwashout rateのcircumferential profile curveを用いた定量的評価法による冠状動脈狭窄病変の診断能を, 視覚的なsegmental analysisを用いた定性的評価法による診断能と比較検討した. 定量的評価法による各冠状動脈の診断精度は, LADで89%, RCAで86%, LCXで87%であり, 定性的評価法による場合の, それぞれ82%, 79%, 79%に比べ, いずれも上昇した. また罹患冠状動脈数の診断率は, 定量的評価法では, 1枝病変で74%, 2枝病変で69%, 3枝病変で80%であり, 定性的評価法による場合の, それぞれ68%, 63%, 30%に比べ, いずれも上昇した. 本法は定性的評価法に比べ, 201Tl心筋ECTによる各冠状動脈狭窄病変の診断率や, 多枝病変, 特に3枝病変の診断率向上のために, 有用と思われた.
Practice臨床医学:一般
Keywords201Tl myocardial ECT, Coronary artery disease, Circumferential profile analysis, Washout rate.
English
TitleQuantitative Evaluation of Coronary Artery Disease by 201Tl Myocardial Emission Computed Tomography - Evaluation by Circumferential Profile Analysis of Regional Distribution and Washout Rate -
SubtitleOriginal Articles
AuthorsTsunao ITO*, Kan TAKEDA*, Hisato MAEDA*, Tsuyoshi NAKAGAWA*, Nobuo YAMAGUCHI*, Katsutoshi MAKINO**, Yasuo FUTAGAMI**, Tokuji KONISHI**
Authors(kana)
Organization*Department of Radiology, **First Department of Internal Medicine, Mie University School of Medicine
JournalThe Japanese Journal of nuclear medicine
Volume23
Number1
Page43-53
Year/Month1986/1
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
AbstractThe purpose of this study is to investigate the value of quantitative evaluation by circumferential profile analysis of stress-redistribution myocardial 201Tl distribution and myocardial 201Tl washout to diagnose coronary artery disease in comparison with qualitative evaluation by visual segmental analysis, using emission computed tomography (ECT). In 14 normal cases and 57 cases with angiographically defined coronary artery disease, stress and redistribution ECT were performed. ECT data were acquired in a 64×64 matrix format from 90 projections over 360 degrees using an ECT system with dual opposed large-field gamma cameras. A total acquisition time was 6 minutes. Tomographic sections oriented perpendicular and parallel to the long axis of left ventricule were reconstructed. For qualitative evaluation, ECT myocardial images were divided into 8 segments and segmental analysis was made by visual interpretation. For quantitative evaluation, circumferential profile curves for stress-redistribution myocardial 201Tl distribution and myocardial 201Tl washout were generated and evaluated by comparing with normal limits, which were obtained from 14 normal cases. Quantitative evaluation showed superior diagnostic accuracies to qualitative evaluation in left anterior descending artery (from 82% to 89%), right coronary artery (from 79% to 86%) and left circumflex artery (from 79% to 87%) lesions. Moreover, the number of diseased coronary arteries was more accurately predicted by quantitative evaluation. Especially in patients with threevessel disease, 80% of the patients was detected accurately by the quantitative evaluation, while only 30% by the qualitative evaluation. We conclude that this quantitative evaluation for 201Tl myocardial ECT produces a remarkable improvement for predicting individual coronary artery disease and number of diseased coronary arteries.
PracticeClinical medicine
Keywords201Tl myocardial ECT, Coronary artery disease, Circumferential profile analysis, Washout rate.

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