| Japanese |
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| Title | ファースト・パス法における濃度補正の研究 - 基礎的研究および右室駆出率への適応 - |
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| Subtitle | 原著 |
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| Authors | 岩田和朗*, 筒井重治*, 芝辻洋*, 居出弘一*, 吉村均*, 本田泰啓*, 浜田信夫* |
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| Authors(kana) | |
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| Organization | *奈良県立医科大学腫瘍放射線科 |
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| Journal | 核医学 |
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| Volume | 23 |
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| Number | 1 |
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| Page | 1-8 |
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| Year/Month | 1986/1 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」ファースト・パス法を用いて駆出率(EF)を算出する際, RI-tracerの時間的濃度変化は誤差の要因となる. この濃度変化の影響をなくすため, ガンマ変量を用いた濃度補正法(GA法)を考案し, 従来のbeat to beat(B-B法)と比較検討した. 解析には心血行動態ファントームを用い, 基礎的研究を行った. その結果, RI注入時間が短い場合, 心拍ごとのEFの変動(Range)および平均EFの相対誤差は, B-B法に比べてGA法の方が有意に低値となった. また, 臨床例ではRIを急速に注入した10症例について, 隣接する2心拍のそれぞれの右室駆出率(RVEF)を求め比較検討した. その結果, B-B法では最初の心拍のRVEF(42.3±9.2%)の方が2番目のRVEF(51.7±4.9%)より有意に小さくなったが, GA法では各RVEF間(52.0±8.0%, 51.3±4.3%)に有意差は見られなかった. GA法は, 濃度変化の影響をなくし, RVEFの算出に有効な方法である. |
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| Practice | 臨床医学：一般 |
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| Keywords | First pass method, Right ventricular ejection fraction, Concentration correction. |
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| English |
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| Title | Study of Concentration Correction for the First Pass Method - Application to Right Ventricular Ejection Fraction - |
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| Subtitle | Original Articles |
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| Authors | Kazuro IWATA, Shigeharu TSUTSUI, Hiroshi SHIBATSUJI, Koichi IDE, Hitoshi YOSHIMURA, Yasuhiro HONDA, Nobuo HAMADA |
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| Authors(kana) | |
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| Organization | Department of Oncoradiology, Nara Medical University |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 23 |
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| Number | 1 |
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| Page | 1-8 |
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| Year/Month | 1986/1 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | The determinations of ejection fraction (EF) by the common first pass beat to beat method (B-B method) are subjected to errors attributable to the effect of rapid inflow or outflow of radionuclide tracer i.e., the effect of time-varying concentration of the tracer. In order to attenuate the effect of time-varying concentration, a new method was developed by using gamma variate function (GA method). In laboratory experiments, the Range of EF/beat and the relative error of EF obtained from B-B method are large in the case of short injection time of radionuclide tracer, while those obtained from GA method are smaller regardless of injection time. In clinical studies, the first RVEF/beat obtained from B-B method is significantly smaller than the second, while there is no significant difference between those two RVEF/beat obtained from GA method. We conclude that the determinations of RVEF by using GA method are more stable and precise than those by B-B method. |
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| Practice | Clinical medicine |
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| Keywords | First pass method, Right ventricular ejection fraction, Concentration correction. |
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