| Japanese |
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| Title | 冠動脈一枝病変の評価 : 無侵襲性検査による検出率とPercutaneous Transluminal Coronary Angioplasty成功例の検討 |
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| Subtitle | 原著 |
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| Authors | 大島統男*, Steven C. PORT**, Gautam RAY**, Patrick MCNAMEE**, Donald H. SCHMIDT** |
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| Organization | *岐阜県立多治見病院放射線科, **University of Wisconsin Medical School, Mount Sinai Medical Center |
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| Journal | 核医学 |
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| Volume | 22 |
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| Number | 12 |
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| Page | 1799-1808 |
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| Year/Month | 1985/12 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」 本研究の目的は冠動脈一枝病変 (70%以上狭窄を示すもの) において通常施行されている種々の運動負荷検査のsensitivityとpercutaneous transluminal coronary angioplasty (PTCA) 施行後の改善度とを調べることにある. 冠動脈一枝病変を示しかつ心筋梗塞の既往のない群 (56例) において運動負荷による無侵襲検査を施行した. 運動負荷ECGは, 34人において明らかな異常を示した (61%) . Tl-201 planarによる定性的評価では50人において異常を示し (89%) , 定量的評価 (断層像) では48人において異常を示した (86%) . 運動負荷駆出率が56%以下または新しい壁運動の異常を示したものが38人あった (68%) . PTCA施行前後の群 (22例) は以下のごとくであった. 運動負荷ECGはPTCA前は13/22 (59%) において異常を示しPTCA後は5/22 (23%) と改善した. Tl-201によるplanarと断層像の検出率はPTCA前は21/22 (95%) と20/22 (91%) であり, PTCA後は各13/22 (59%) と15/22 (68%) に改善した. さらにRIアンジオはPTCA前は15/22 (68%)において異常であったが, PTCA後は5/22 (23%) に改善した. 以上の結果から運動負荷心筋シンチグラムは冠動脈一枝病変の最もsensitiveな無侵襲検査であることを示している. 運動負荷ECGとRIアンジオは, PTCA前の虚血を検出するうえで心筋シンチグラムよりsensitivityが劣るが, PTCA後の改善度の検出率では優る結果となった. |
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| Practice | 臨床医学：一般 |
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| Keywords | Single vessel disease, Percutaneous transluminal coronary angioplasty, Exercise scintigraphy |
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| English |
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| Title | Assessment of Single Vessel Coronary Artery Disease : Results of Non-Invasive Tests and Evaluation after Successful Percutaneous Transluminal Coronary Angioplasty |
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| Subtitle | Original Articles |
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| Authors | Motoo OSHIMA*, Steven C. PORT**, Gautam RAY**, Patrick MCNAMEE**, Donald H. SCHMIDT** |
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| Authors(kana) | |
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| Organization | *Gifu Kenritsu Tajimi Hospital, **University of Wisconsin Medical School, Mount Sinal Medical Center |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 22 |
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| Number | 12 |
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| Page | 1799-1808 |
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| Year/Month | 1985/12 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] The purpose of this study was to determine the sensitivities of noninvasive tests for the diagnosis of single vessel coronary artery disease in a group of 56 patients with no infarction. Among these patients, 22 patients who underwent successful percutaneous transluminal angioplasty (PTCA) were also evaluated with non-invasive tests. The non-invasive tests were : twelve-lead electrocardiography, thallium-201 perfusion imaging (both planar and seven-pinhole tomographic) and radionuclide angiography. Electrocardiography and thallium imaging were performed during the same graded treadmill exercise while the radionuclide angiography was performed during upright bicycle exercise. Exercise electrocardiograms were abnormal in 34/56 patients (61%) . Qualitative planar thallium images were abnormal in 50/56 patients (89%) . Quantitative analysis of the tomographic thallium images was abnormal in 49/56 patients (86%) . An exercise ejection fraction<0.56 or a new wall motion abnormality was seen in 38/59 patients (68%) . The results suggest that exercise thallium-201 myocardial scintigram is the most sensitive noninvasive stress test for the diagnosis of single vessel coronary artery disease. Exercise ECG and RI angiography showed less sensitive for detecting ischemia pre-PTCA than thallium-201, however, showed great trend toward normalization post-PTCA. |
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| Practice | Clinical medicine |
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| Keywords | Single vessel disease, Percutaneous transluminal coronary angioplasty, Exercise scintigraphy |
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