| Japanese |
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| Title | 脳血管障害患者における, N-isopropyl-p- [123I] -iodoamphetamineによる脳血流シンチグラフィ |
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| Subtitle | 原著 |
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| Authors | 曽根照喜*, 福永仁夫*, 大塚信昭*, 村中明*, 柳元真一*, 友光達志*, 森田陸司*, 梶原康正*, 西下創一*, 小野志磨人**, 寺尾章**, 佐藤雅春***, 小浜啓次*** |
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| Authors(kana) | |
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| Organization | *川崎医科大学核医学科, 放射線科, **神経内科, ***救急部 |
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| Journal | 核医学 |
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| Volume | 22 |
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| Number | 10 |
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| Page | 1447-1459 |
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| Year/Month | 1985/10 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」 脳血管障害20例に対して, N-isopropyl-p- [123I] -iodoamphetamine (123I-IMP) による脳血流シンチを施行し, 回転型ガンマ・カメラによりその断層像を得て, X線CTや血管造影の所見と比較, 検討した. 123I-IMPによる検査では14例で局所的な血流の低下が検出され, X線CTの成績 (14例検出) とほぼ同等であった. しかし, 脳の機能障害の正確な範囲を把握するには, 123I-IMPによる検査はきわめて有用で, 神経学的所見と一致する部位に血流の低下が認められた. さらに小脳出血やRINDではX線CTで異常が指摘できなかったのに対し, 123I-IMPで集積の低下が観察された. 血管造影で血管の狭窄や異常血管が観察されても, 脳実質の血流変化を伴うとは限らないことが, 椎骨脳底動脈循環不全例やvenous angioma例で明らかにされた. 123I-IMPによる脳血流シンチは脳の局所血流の状態を正確に知る上で非常に有用な非侵襲的な方法であり, しかも安全に施行できることが示された. |
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| Practice | 臨床医学：一般 |
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| Keywords | 123I-IMP, Cerebrovascular accident, Cerebral blood flow |
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| English |
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| Title | Scintigraphy of Cerebral Blood Flow with N-isopropyl-p- [123I] -iodoamphetamine in Cerebrovascular Accident |
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| Subtitle | Original Articles |
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| Authors | Teruki SONE*, Masao FUKUNAGA*, Nobuaki OTSUKA*, Akira MURANAKA*, Shinichi YANAGIMOTO*, Tatsushi TOMOMITSU*, Rikushi MORITA*, Yasumasa KAJIHARA*, Souichi NISHISHITA*, Shimato ONO**, Akira TERAO**, Masaharu SATOH***, Akitsugu KOHAMA*** |
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| Authors(kana) | |
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| Organization | *Department of Nuclear Medicine, Radiology, **Department of Neurology, ***Department of Emergency Medicine, Kawasaki Medical School |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 22 |
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| Number | 10 |
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| Page | 1447-1459 |
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| Year/Month | 1985/10 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] In 20 patients with cerebrovascular accident, cerebral blood now was estimated with N-isopropyl-p- [123I] -iodoamphetamine (123I-IMP) using a rotating gamma camera, and the findings were compared with those of X-CT or angiography. 123I-IMP study demonstrated the areas of diminished cerebral blood flow in 14 cases. X-CT also demonstrated lesions in 14 cases, however, 123I-IMP study delineated the lesions more precisely corresponding to the neurological findings. In cases with cerebellar hemorrhage or reversible ischemic neurological deficit (RIND) , the lesion could be established only by 123I-IMP study. It was demonstrated by 123I-IMP study that vascular stenosis or abnormal vessels seen on angiography in patients with vertebro-basilar insufficiency or venous angioma was not necessarily accompanied by diminished blood flow. It was shown that scintigraphy with 123I-IMP was a non-invasive, safe and extremely useful method to estimate the regional cerebral blood flow. |
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| Practice | Clinical medicine |
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| Keywords | 123I-IMP, Cerebrovascular accident, Cerebral blood flow |
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