| Japanese |
|---|
| Title | Duchenne型進行性筋ジストロフィ症における心筋症の201Tl心筋SPECT |
|---|
| Subtitle | 原著 |
|---|
| Authors | 陣之内正史*, 浅井順子**, 井上謙次郎**, 星博昭***, 渡辺克司*** |
|---|
| Authors(kana) | |
|---|
| Organization | *国立療養所宮崎東病院放射線科, **内科, ***宮崎医科大学放射線医学教室 |
|---|
| Journal | 核医学 |
|---|
| Volume | 22 |
|---|
| Number | 9 |
|---|
| Page | 1353-1359 |
|---|
| Year/Month | 1985/9 |
|---|
| Article | 原著 |
|---|
| Publisher | 日本核医学会 |
|---|
| Abstract | 「要旨」 安静時201Tl心筋SPECTをDuchenne型進行性筋ジストロフィ症 (DMD, n=14) に施行し, 定性的および定量的に心筋障害の評価を行った. SPECT像の定性的評価では, 低灌流域を認めたものは14例中10例 (71%) で全例13歳以上であり, 部位別では後壁10例 (71%) , 下壁8例 (57%) , 側壁および前壁各6例 (43%) , 心尖部2例 (14%) , 中隔1例 (7%) であった. 加齢や骨格筋障害度の進行とともに, 範囲の広がる傾向がみられたが, 相関は見られなかった. ファントム実験をもとにした定量的評価では, 201Tl心筋摂取率は3.6±1.0% (対照群n=8, 2.7±0.3% : p<0.05) , 左室心筋容積は190.2±67.5ml (対照群157.8±21.5ml:n.s.) であった. 年齢, 骨格筋障害度との相関はみられなかった. DMDの心筋病変は症例ごとに違いがあり, その病態把握に201Tl心筋SPECTが有用であると思われた. |
|---|
| Practice | 臨床医学：一般 |
|---|
| Keywords | Duchenne muscular dystrophy, Cardiomyopathy, Tl-201 myocardial SPECT, Tl-201 myocardial uptake ratio, Left ventricular muscle volume |
|---|
| English |
|---|
| Title | Evaluation of Cardiomyopathy in Duchenne Muscular Dystrophy by Tl-201 Myocardial SPECT |
|---|
| Subtitle | Original Articles |
|---|
| Authors | Seishi JINNOUCHI*, Junko ASAI**, Kenjirou INOUE**, Hiroaki HOSHI***, Katsushi WATANABE*** |
|---|
| Authors(kana) | |
|---|
| Organization | *Department of Radiology, **Department of Internal Medicine, Miyazaki Higashi Byoin National Sanatorium, ***Department of Radiology, Miyazaki Medical College |
|---|
| Journal | The Japanese Journal of nuclear medicine |
|---|
| Volume | 22 |
|---|
| Number | 9 |
|---|
| Page | 1353-1359 |
|---|
| Year/Month | 1985/9 |
|---|
| Article | Original article |
|---|
| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
|---|
| Abstract | [Summary] Clinical evaluation of Tl-201 myocardial SPECT in patients with cardiomyopathy of Duchenne type progressive muscular dystrophy (DMD) was reported. Cases subjected to study were 14 DMD and 8 normal Using a rotating gamma camera system (ZLC7500 and Scintipac 70A) , SPECT data were collected for 16 minutes (32 angles×30 sec/angle, 180°) . The hypoperfusion areas of the left ventricular muscle were observed in 10 patients (71%) , which was in posterior wall (71%) , inferior wall (57%) , lateral and anterior wall (43%) in the order of frequency. The hypoperfusion area became wider with age and stage, exept for some patients. It was suggested that myocardial degeneration in DMD started in posterior wall and then spread in other areas. For the purpose of quantitative evaluation of myocardial damage, Tl-201 myocardial uptake ratio (MUR) and left ventricular muscle volume (LVMV) were calculated using the results obtained by phantom studies. MUR and LVMV were higher in DMD than those of normal individuals (3.6+-1.0% : 2.7+-0.3%, p<0.05, 190.2+-67.5ml : 157.8+-21.5ml, n.s., respectively) . |
|---|
| Practice | Clinical medicine |
|---|
| Keywords | Duchenne muscular dystrophy, Cardiomyopathy, Tl-201 myocardial SPECT, Tl-201 myocardial uptake ratio, Left ventricular muscle volume |
|---|