| Japanese |
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| Title | 99mTc-DTPAおよび131I-Orthoiodohippurate同時投与によるRenogramの検討 - 分腎GFR, ERPFおよびRetention Functionの算出 - |
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| Subtitle | 原著 |
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| Authors | 前田盛正*, 長谷川隆**, 田中州鶴**, 吉田博** |
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| Organization | *元大阪鉄道病院放射線科, **大阪鉄道病院放射線科 |
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| Journal | 核医学 |
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| Volume | 22 |
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| Number | 9 |
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| Page | 1341-1352 |
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| Year/Month | 1985/9 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」 99mTc-DTPAと131I-OIHの同時投与によって, renogramを作成し, 腎の初期摂取率から分腎ERPFおよびGFRを推定するとともに, 30分膀胱排泄率と腎の初期摂取率の左右比からも分腎ERPFおよびGFRを算出した. 腎の初期摂取率によるものと膀胱排泄率によるものとはいずれも良好な相関を示した. また両放射性薬剤のrenogramと大動脈曲線から, retention functionをmatrix法によるdeconvolutionによって解き, H (1) およびMTTを求めた. それぞれのH (1) は分腎ERPFおよびGFRと良好な正の相関を示したが, MTTでは負の相関で相関係数は低いという結果を得た. 腎およびBGのROIのとり方について考察した. 131I-OIHではROIのとり方による影響は少ないが, 99mTc-DTPAでは腎に近接したROIが必要で, われわれは辺縁増強法と30% cut offの方法を用いた. BGのROIとして, 円弧と円周とを比較検討したが, subtraction後のrenogramの形は円弧の方が原型に近く, パターン認識の大切なrenogram検査では円弧の方がよいと考える. |
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| Practice | 臨床医学：一般 |
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| Keywords | 99mTc-DTPA renogram, 131I-OIH renogram, GFR, ERPF, Retention function |
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| English |
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| Title | Analysis of Renograms with Simultaneous Injection of 99mTc-DTPA and 131I-OIH - Estimation of GFR, ERPF and Retention Function of Individual Kidney - |
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| Subtitle | Original Articles |
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| Authors | Morimasa MAEDA*, Ryu HASEGAWA**, Shukaku TANAKA**, Hiroshi YOSHIDA** |
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| Authors(kana) | |
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| Organization | *元大阪鉄道病院放射線科, **Department of Radiology, JNR Osaka Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 22 |
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| Number | 9 |
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| Page | 1341-1352 |
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| Year/Month | 1985/9 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Renograms obtained by the simultaneous injection of 131I-OIH and 99mTc-DTPA were analyzed. Separate ERPF and GFR of individual kidneys were calculated using two methods ; the early phase uptake rate in the kidney and the 30-minute excretion rate in the bladder. The values of ERPF and GFR obtained from the two methods showed good correlation between both radiopharmaceuticals. Retention function was then calculated using matrix deconvolution after aortic blood background subtraction. Values of H (1) showed good correlation with ERPF and GFR, respectively. However, values of MTT showed rather poor correlation with ERPF and GFR, especially the latter. The influence of the region of interest (ROI) configuration on the kidney and background was then discussed. The size and form of ROI for the kidney and background have a considerable effect on the 99mTc-DTPA renogram, although they have a little effect on the 131I-OIH renogram. Configuration of ROI over the kidney should fit close to the real edge of the organ. We tried to use a combination of double differentiation (edge enhancement) and 30% cut off method for ROI over the kidney. For the background, we prefer arcuated to circular ROI because the renogram obtained by the former method is more similar to the original renogram which is important for its subsequent analysis. |
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| Practice | Clinical medicine |
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| Keywords | 99mTc-DTPA renogram, 131I-OIH renogram, GFR, ERPF, Retention function |
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