| Japanese |
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| Title | 最大エントロピー法による肝血流動態の評価 |
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| Subtitle | 原著 |
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| Authors | 瀬尾信也*, 阿部由直**, 山田健嗣**, 吉岡清郎**, 松澤大樹**, 佐々木雄一郎* |
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| Organization | *南町クリニック, **東北大学抗酸菌病研究所放射線医学部門 |
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| Journal | 核医学 |
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| Volume | 22 |
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| Number | 9 |
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| Page | 1333-1340 |
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| Year/Month | 1985/9 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」 肝シンチグラフィーから得られる時間放射能曲線を最大エントロピー法で周波数解析することにより, 肝臓への入力である肝動脈成分と門脈成分の分離を試みた. 肝動脈成分を示すと考えられる早い周期をFast Cycle (FC) , 門脈成分を示すと考えられる遅い周期をSlow Cycle (SC) とした. これらの値を用いて正常肝臓群と肝硬変群との間で評価を行った. この結果, 肝臓の周期を腎臓の周期で割った値は, FCで正常群は0.904±0.14, 肝硬変群は0.662±0.16 (p<0.05) , SCで正常群は1.08±0.11, 肝硬変群は1.65±0.35 (p<0.005) となった. このように正常群と肝硬変群の血流動態を周期の違いとして評価することができ, 臨床的に有用であると考えられる. |
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| Practice | 臨床医学：一般 |
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| Keywords | 99mTc-phytate, Liver scintigraphy, Spectrum analysis, Maximum entropy methods. Liver cirrhosis |
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| English |
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| Title | Evaluation of Hepatic Blood Flow Using Maximum Entropy Methods |
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| Subtitle | Original Articles |
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| Authors | Shinya SEO*, Yoshinao ABE**, Kenji YAMADA**, Seiro YOSHIOKA**, Taiju MATSUZAWA**, Yuichiro SASAKI* |
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| Organization | *Minamimachi Clinic, **Department of Radiology and Nuclear Medicine, Research Institute for Tuberculosis and Cancer, Tohoku University |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 22 |
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| Number | 9 |
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| Page | 1333-1340 |
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| Year/Month | 1985/9 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Using spectrum analysis (Maximum entropy methods ; MEM) , we separated the portal venous and the hepatic arterial components from the time activity curve (TAC) obtained by RI angiography of 99mTc-phytate. We set the region of interest on the right lobe of the liver and the left kidney, and set the short and the long section to the differentiated TAC of the liver and the TAC of the kidney. Sectioning was done as follows : 1) short section, from the point at 20% of the peak to the point at the peak of the kidney. 2) long section, from the point at 20% of the peak to the point at 0 which was extrapolated from the initial slope of the TAC of the kidney. We analysed these sections using MEM. The fast cycle (FC) obtained from the short section was related to the mean transit time (MTT) of the hepatic artery. The slow cycle (SC) obtained from the long section was related to the MTT of the portal vein. FC and SC were calculated on the liver and the kidney. Clinically, we compared the normal liver with liver chirrhosis. In normal, the liver to kidney ratio of FC and SC were 0.90+-0.14 and 1.08+-0.11, respectively. In cirrhosis, the liver to kidney ratio of FC and SC were 0.66+-0.16 and 1.65+-0.35, respectively. These results were reasonable for the hemodynamics of the diseased liver. |
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| Practice | Clinical medicine |
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| Keywords | 99mTc-phytate, Liver scintigraphy, Spectrum analysis, Maximum entropy methods. Liver cirrhosis |
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