Japanese
Title心RI first pass法による陳旧性心筋梗塞症の左室拡張機能障害の評価 - フーリエ近似曲線を用いた検討 -
Subtitle原著
Authors小糸仁史*, 岩坂壽二*, 吉岡廣*, 木村穣*
Authors(kana)
Organization*関西医科大学第二内科
Journal核医学
Volume22
Number7
Page999-1011
Year/Month1985/7
Article原著
Publisher日本核医学会
Abstract「要旨」陳旧性心筋梗塞症の左室拡張機能を評価する目的で対照群58例, OMI-1群 (EF≧55%) 64例, OMI-2群 (EF<55%) 77例にmulticrystal cameraを用いて心RI first pass法を施行した. 左室容積曲線にフーリエ解析を行いフーリエ1次および2次近似曲線を用いたresurge curveからDEおよびDLを, フーリエ4次近似曲線より拡張期前1/3充満分画および拡張期後1/3充満分画を算出し左室拡張機能の指標とした. LVEDVおよび左室収縮機能の指標であるLVEF, CO, SVはOMI-1群と対照群に差はなかった. しかし, 左室拡張機能の指標は対照群, OMI-1群, OMI-2群の順で有意にDEは大きく, DLは小さく, 拡張期前1/3充満分画は大きくなった. これより, 左室収縮機能に障害を示さない陳旧性心筋梗塞症でも拡張早期の左室充満が障害されていることを示し, 拡張機能の指標は陳旧性心筋梗塞症の心機能障害の評価に有用と考えられた.
Practice臨床医学：一般
KeywordsRadionuclide angiocardiography, Myocardial infarction, Left ventricular diastolic property, Fourier analysis
English
TitleFirst Pass Radionuclide Angiocardiographic Assessment of Left Ventricular Diastolic Function in the Patients with Old Myocardial Infarction
SubtitleOriginal Articles
AuthorsHitoshi KOITO, Toshiji IWASAKA, Hiroshi YOSHIOKA, Yutaka KIMURA
Authors(kana)
OrganizationSecond Department of Internal Medicine, Kansai Medical University
JournalThe Japanese Journal of nuclear medicine
Volume22
Number7
Page999-1011
Year/Month1985/7
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] To assess the resting left ventricular diastolic function in the patients with old myocardial infarction (OMI) , we analyzed global left ventricular volume curve obtained by first pass Tc-99m angiocardiography with Fourier analysis. Control group consisted of 11 patients with neurocirculatory asthenia (NCA) and 47 patients with angina pectoris (AP) , and OMI groups are divided into two groups (OMI-1, 64 cases with LVEF>=55% and OMI-2, 77 cases with LVEF<55%) . The resurge curve was constructed from the first and 2 harmonics approximation curve of Fourier analysis. The tangential slopes at midpoint of an early half (DE) and a late half (DL) of the diastolic phase in the resurge curve were used as the indexes of left ventricular diastolic function. Early 1/3 filling fraction (EFF) and late 1/3 filling fraction (LFF) in 4 harmonics Fourier approximation curve were also used as the indexes. CO, SV and LVEDV in OMI-1 (3.9+-0.9l/min, 60+-12ml and 93+-19ml, respectively) did not differ from those in control group (3.9+-0.8l/min, 60+-13ml and 90+-17ml) . The significant diminution in CO and SV, and the increase in LVEDV were observed in OMI-2 (3.5+-1.0l/min, 48+-13ml and 139+-47 ml) . On the other hand, DE (0.69+-0.14, 0.80+0.18 and 1.25+-0.35 in control, OMI-1 and OMI-2, respectively) , DL (2.31+-0.92, 1.74+-0.67 and 1.07+-0.38) , EFF (43+-13%, 37+-14% and 26+-11%) and LFF (24+-7%, 26+-9% and 38+-12%) were significantly different among these three groups. The results suggest that the patients with OMI-1 have abnormal left ventricular diastolic function in spite of normal systolic function expressed by LVEF, CO, SV and LVEDV. We conclude that assessment of left ventricular diastolic function is useful for early diagnosis of cardiac functional abnormality in the patients with old myocardial infarction.
PracticeClinical medicine
KeywordsRadionuclide angiocardiography, Myocardial infarction, Left ventricular diastolic property, Fourier analysis

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