Japanese
Title運動負荷心筋スキャンにおける健常心筋部位のwashout rateに関する検討
Subtitle原著
Authors西村恒彦*, 植原敏勇*, 林田孝平*, 小塚隆弘*, 斉藤宗靖**, 住吉徹哉**
Authors(kana)
Organization*国立循環器病センター放診部, **内科
Journal核医学
Volume22
Number7
Page989-997
Year/Month1985/7
Article原著
Publisher日本核医学会
Abstract「要旨」運動負荷心筋スキャンにおいて, 一過性欠損像の検出が困難な症例がある. このような症例に, washout rate法の併用は虚血の検出に有用である. しかし, 正常例, 1, 2枝病変 (狭心症) の健常心筋部位において, 時に心筋全体のwashout rateの低下 (Diffuse slow washout) をみることがある. そこで, これらの症例において, washout rateの算出に影響する因子について検討した. 正常100例においてwashout rateと負荷時最大心拍数はr=0.721, また肺野タリウム活性とはr=-0.56の相関を示し, 両者と密接な関係があることが示された. また, 1枝病変33例中6例 (18%) , 2枝病変30例中8例 (24%) においてDiffuse slow washoutを認めた. これらの症例では, 肺野のタリウム活性の増加, 負荷量の不足 (心拍数の低下) を有意に認めた. したがって, 心筋washout rateによる虚血の検出を行う際, 本現象に留意すべきである.
Practice臨床医学:一般
KeywordsWashout rate, Peak heart rate, Lung thallium uptake, Stress thallium scan, Diffuse slow washout
English
TitleEvaluation of Washout Rate in Healthy Myocardium Using Stress Thallium Scan
SubtitleOriginal Articles
AuthorsTsunehiko NISHIMURA, Toshiisa UEHARA, Kohei HAYASHIDA, Takahiro KOZUKA, Muneyasu SAITO, Tetsuya SUMIYOSHI
Authors(kana)
OrganizationDepartment of Radiology and Cardiac Unit, National Cardiovascular Center
JournalThe Japanese Journal of nuclear medicine
Volume22
Number7
Page989-997
Year/Month1985/7
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] The interpretation of stress thallium scan was performed ordinally by transient defect analysis using initial and delayed image. In addition, relative quantification of stress thallium scan has recently developed using wahout rate analysis for the detection of ischemia. However, we sometimes observed diffuse slow washout (DSWO) in normal cases and healthy myocardial region in angina pectoris (single and double vessel diseases) without myocardial infarction. Therefore, we evaluated the factor influencing washout rate in 100 normal cases and angina pectoris (33 single and 30 double vessel disease) . Washout rate was calculated from circumferential profile analysis using initial and delayed image. In normal cases, washout rate was closely related to peak heart rate (r=0.72) and inversely related to lung thallium uptake (r=-0.56) respectively. In addition, DSWO was observed in 6 (18%) of 33 single and 8 (24%) of 30 double vessel diseases. And, the patients with DSWO showed significantly higher lung thallium uptake and lower peak heart rate (p<0.01) compared to those without DSWO. In conclusion, these data should be considered in the interpretation of stress thallium scan by washout rate analysis.
PracticeClinical medicine
KeywordsWashout rate, Peak heart rate, Lung thallium uptake, Stress thallium scan, Diffuse slow washout

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