Japanese
Title運動負荷心筋シンチグラムより求めたWashout Rate (WR)による冠動脈病変の重症度判定
Subtitle短報
Authors津田隆志*, 小島研司*, 閏間美智子*, 古寺邦夫*, 林千治*, 渡辺賢一*, 相沢義房*, 荒井裕*, 柴田昭*, 浜斎**, 三谷亨**
Authors(kana)
Organization*新潟大学医学部第一内科, **木戸病院RI室
Journal核医学
Volume22
Number3
Page383-388
Year/Month1985/3
Article報告
Publisher日本核医学会
Abstract「I. はじめに」最近の心臓核医学の進歩により, 運動負荷を用いたタリウム心筋シンチグラフィー (以下「負荷シンチ」と略す) は, 冠動脈疾患の診断に必要不可欠な方法として定着しつつある. また, 各種の定量評価法が, 冠動脈疾患の検出におけるSensitivity, Specificityの向上に貢献している. ところで, 冠動脈病変の存在診断に対する多くの定量評価法の利用が行われているにもかかわらず, 冠動脈病変の重症度判定に対するそれらの利用の報告は少ない. 今回, われわれは多枝病変の検出等に用いられている局所心筋のWashout Rate (WR)を求め, 冠動脈病変の狭窄度との関係を検討し, 良好な結果が得られたので報告する.
Practice臨床医学:一般
KeywordsExercise myocardial scintigraphy, Coronary artery disease, Severity of coronary artery lesion, Washout rate
English
TitleSeverity of Coronary Artery Lesion by Washout Rate (WR) in Exercise Myocardial Scintigraphy
Subtitle
AuthorsTakashi TSUDA*, Kenji OJIMA*, Michiko URUMA*, Kunio KODERA*, Senji HAYASHI*, Kenichi WATANABE*, Yoshifusa AIZAWA*, Yutaka ARAI*, Akira SHIBATA*, Hitoshi HAMA**, Tohru MITANI**
Authors(kana)
Organization*The First Department of Internal Medicine, Niigata University School of Medicine, **Kido Hospital
JournalThe Japanese Journal of nuclear medicine
Volume22
Number3
Page383-388
Year/Month1985/3
ArticleReport
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] The quantitative estimation of exercise myocardial scintigraphy has increased the diagnostic value of coronary artery lesions, but it has not been used for the evaluation of the severities. In this study, the relationship between the severities and WR with exercise myocardial scintigraphy was discussed. The patients had stenosis in proximal left anterior descending artery and were classified in three groups. Group I containted seven patients who had less than 50% stenosis in diameter, group II contained seven who had 75% stenosis and group III contained nine who had more than 90%stenosis. Twelve normal persons were used as control. WR of anteroseptal wall in LAO 45°view was evaluated. The values of WR were 27.3+-10.2% (Mean+-SD) in control, 14.4+-13.8%in group I, 11.6+-10.7%in group II and -0.5+-10.2% in group III, respectively. As stenosis became severer, WR showed significantly lower value compared with control (p<0.05-0.001) . There was significant difference in WR between group I and group III (p<0.05) and between group II and group III (p<0.05) , respectively. We conclude that WR is effective index in evaluation of severity of coronary lesions, though it is related to the workload because of a fair correlation found between WR and peak heart rate at exercise (r=0.466) .
PracticeClinical medicine
KeywordsExercise myocardial scintigraphy, Coronary artery disease, Severity of coronary artery lesion, Washout rate

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