| Japanese |
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| Title | 人工透析者の骨シンチグラムの分類 |
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| Subtitle | 原著 |
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| Authors | 石橋一成*, 宮前達也** |
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| Organization | *埼玉医科大学第二内科, **放射線科 |
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| Journal | 核医学 |
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| Volume | 22 |
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| Number | 3 |
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| Page | 367-376 |
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| Year/Month | 1985/3 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」人工透析者75例の99mTc-MDPによる骨シンチグラムは, 視覚的に, 軟部組織への取り込みが高く骨への取り込みの低いI群 (56例) と, 逆に軟部組織に低く骨に高いII群 (19例) に分類することができた. さらに, I群の中で, 関節周囲への取り込みの比較的高いIA群 (関節型21例) と, 骨全体に低いIB群 (低下型35例) に分類できた. また, II群の中でも, 特に脊椎への取り込みの高いIIA群 (脊椎型14例) と, 頭部顔面に高いIIB群 (頭部顔面型5例) に分類できた. さらに, 透析者全例と正常骨シンチグラム群146例について, 頭蓋骨, 顎骨, 腰椎, 大腿骨の骨一軟部組織比 (B/S ratio) と, 大腿骨の骨端一骨幹比 (E/D ratio) を求め比較検討した. 正常群と比べ, 各部位のB/S ratioは, I群で低くII群で高く, E/D ratioはIA群で著高を認めた. 組織生化学的に, IA群は骨軟化症, II群は2次性副甲状腺機能亢進症が考えられた. 以上の, 視覚的分類, 半定量的検討は, 腎性骨異栄養症の病態評価上有効と思われた. |
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| Practice | 臨床医学：一般 |
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| Keywords | 99mTc-MDP, Bone scintigram, Renal osteodystrophy, Osteomalacia, Secondary hyperparathyroidism |
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| English |
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| Title | Classification of Bone Scintigrams in Hemodialysis Patients |
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| Subtitle | Original Articles |
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| Authors | Kazunari ISHIBASHI*, Tatsuya MIYAMAE** |
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| Organization | *The Second Department of Internal Medicine, **The Department of Radiology, Saitama Medical School |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 22 |
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| Number | 3 |
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| Page | 367-376 |
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| Year/Month | 1985/3 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Bone scintigrams from a total of 75 hemodialysis patients using 99mTc-methylene-diphosphonate (MDP) were classified into two groups ; Group I (56patients) in which the uptake of the radioactivity appeared to be relatively high in the soft tissue and low in the bone, and Group II (19 patients) in which high uptake in the bone and low uptake in the soft tissue were observed. Patients in Group I were further classified into two subgroups ; Group IA (articular type, 21 patients) which was characterized by relatively high uptake into the joint, and Group IB (reduction type, 35 patients) where uptake was faint in the whole region of the bone. The classification of patients in Group II was also performed ; Group IIA (spinal type, 14 patients) where high spinal uptake was observed, and Group II, (cranio-facial type, 5 patients) where high uptake into the cranio-facial region was observed. The results were compared with 146 subjects with normal bone scintigram in terms of the ratio of bone to soft tissue uptake (B/S ratio) for the cranial bone, jaw bone, lumbar vertebra and femoral bone, and the ratio of epiphysis to diaphysis uptake (E/D ratio) for the femoral bone. The B/S ratio was low in Group l and high in Group II for the bone studied, and the E/D ratio was markedly high in Group IA. Histobiochemical examination indicated that patients in Group IA and Group II may have osteomalacia and secondary hyperparathyroidism, respectively. It was considered that the visual classification and semiquantitative study as described here were useful for evaluating the pathological condition of renal osteodystrophy. |
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| Practice | Clinical medicine |
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| Keywords | 99mTc-MDP, Bone scintigram, Renal osteodystrophy, Osteomalacia, Secondary hyperparathyroidism. |
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