Japanese
Title慢性膵炎における膵酵素合成能測定の臨床的有用性
Subtitle原著
Authors鈴木輝雄*, 高瀬泰和*, 佐藤秀明*, 須賀俊博**, 村島義男**
Authors(kana)
Organization*札幌厚生病院放射線科, **消化器内科
Journal核医学
Volume22
Number3
Page299-306
Year/Month1985/3
Article原著
Publisher日本核医学会
Abstract「要旨」慢性膵炎の消化酵素合成能を検討する目的でCaerulein (60ng/kg/2h) , セクレチン (2U/kg/2h) , Se-75-セレノメチオニン (3.0μCi/kg/2h) を点滴静注して, 十二指腸液中に流出する蛋白放射能を経時的に測定した. 内視鏡的逆行性膵胆管造影 (ERCP) を含む諸検査で膵疾患を否定された対照群6例と慢性膵炎7例の計13例に施行した. アミラーゼ, トリプシン排出量に対するSe-75蛋白放射能の比で検討すると, 慢性膵炎ではいずれも対照群より高値を示し, 統計学的に有意差が認められ, 消化酵素の合成能は亢進していると思われた.
Practice臨床医学：一般
KeywordsChronic pancreatitis, Caeruleinsecretin test, Se-75-selenomethionine, Synthesis of pancreatic enzymes
English
TitleClinical Evaluation of Measurement of Pancreatic Enzyme Synthesis Activity in the Chronic Pancreatitis
SubtitleOriginal Articles
AuthorsTeruo SUZUKI*, Hirokazu TAKASE*, Hideaki SATO*, Toshihiro SUGA**, Yoshio MURASHIMA**
Authors(kana)
Organization*Department of Radiology, **Department of Gastroenterogy, Sapporo Kosei Hospital
JournalThe Japanese Journal of nuclear medicine
Volume22
Number3
Page299-306
Year/Month1985/3
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] For the purpose of clinical evaluation of pancreatic synthetic rates, radioactivity of TCA precipitable protein in duodenal juice was measured during intravenous drip infusion of caerulein (60ng/kg/2h) , secretin (2U/kg/2h) and 75Seselenomethionine (3.0μCi/kg/2h) . The tests were performed in 6 control patients and 7 patients with chronic pancreatitis. The ratios of radioactivity to amylase and trypsin activities were significantly higher in chronic pancreatitis than in control. We conclude that this test is useful for the investigation of the chronic pancreatitis.
PracticeClinical medicine
KeywordsChronic pancreatitis, Caeruleinsecretin test, Se-75-selenomethionine, Synthesis of pancreatic enzymes

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