| Japanese |
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| Title | 人体内の放射能の定量的測定 - 全身にうすく分布する放射能の測定法 - |
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| Subtitle | 研究速報 |
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| Authors | 秋山芳久*, 油井信春**, 木下富士美**, 小圷正木**, 伊藤一郎** |
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| Organization | *千葉がんセンター物理室, **核医学診療部 |
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| Journal | 核医学 |
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| Volume | 22 |
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| Number | 2 |
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| Page | 225-228 |
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| Year/Month | 1985/2 |
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| Article | 報告 |
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| Publisher | 日本核医学会 |
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| Abstract | 「I. はじめに」投与した放射性医薬品の全身分布が正確に測定できれば, 臓器の機能の定量的解析をはじめ, 多くの新しい診断情報をもたらす可能性がある. 放射性医薬品は一般には特定臓器に集積するが, これら臓器以外にも全身に薄くバックグラウンドとして分布している. SPECT (Single Photon Emission Computed Tomography) はもともと3次元的な放射能分布が測定可能であり, 全身にわたりSPECT検査を行えば, 原理上は集積臓器はもちろんバックグラウンド部位の放射能も測定できる. ただSPECTから定量的なデータを得るためには, γ線の人体内での吸収や散乱を正確に補正しなければならず最低限, 体輪郭のデータも得る必要がありこれを全身にわたり行うには, かなりの手間がかかる. |
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| Practice | 臨床医学：一般 |
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| Keywords | Quantitative measurement, Whole body, Gamma camera system |
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| English |
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| Title | Measurement of a Radioactive Quantity in a Human Body - Mensuration of a Faintly Distributed Radioactive Quantity Over the whole Body - |
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| Subtitle | |
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| Authors | Yoshihisa AKIYAMA*, Nobuharu YUI**, Fujimi KINOSHITA***, Masaki KOAKUTSU**, Ichiro ITO** |
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| Authors(kana) | |
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| Organization | *Physics Division, Chiba Cancer Center Hospital, **Department of Nuclear Medicine, Chiba Cancer Center Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 22 |
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| Number | 2 |
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| Page | 225-228 |
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| Year/Month | 1985/2 |
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| Article | Report |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Radioactive agents that are administrated to a patient strongly accumulate in some specific organs, and weakly distribute over the whole body. It is necessary to measure the distributed radionuclide quantitatively for biokinetic analysis and calculation of internal radiation absorbed dose. Whole body distribution of a radioactivity can be theoretically obtained by appling the data of SPECT from head to toe. However, in order to apply the SPECT for the quantitative measurement, the correction of photon attenuation and Compton scatter effect is indispensable, but this is very troublesome. We have investigated a convenient method for quantitative measurement of whole body distribution of a radioactive agent using a dual-head gamma camera system which has ability of conventional localized imaging, whole body imaging and SPECT. The whole body radioactive quantity is measured by the following method. The quantity of radioactive material accumulated in target organs are computed by using the data of SPECT. The quantity of radioactivity which distributed weakly over the whole body is computed by using the data of digitized whole body transmission and emission images. In this paper, the latter is mentioned mainly. |
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| Practice | Clinical medicine |
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| Keywords | Quantitative measurement, Whole body, Gamma camera system |
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