| Japanese |
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| Title | 虚血性心疾患における運動負荷201Tl全身シンチグラフィの臨床的有用性についての検討 |
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| Subtitle | 原著 |
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| Authors | 金子堅三*, 渡辺佳彦*, 近藤武*, 加藤善久*, 桐山卓三*, 桜井充*, 黒川洋*, 菱田仁*, 水野康*, 竹内昭**, 古賀佑彦** |
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| Organization | *藤田学園保健衛生大学内科, **放射線科 |
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| Journal | 核医学 |
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| Volume | 22 |
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| Number | 2 |
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| Page | 209-217 |
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| Year/Month | 1985/2 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」正常 (N) 群12例, 狭心症 (AP) 群19例, 心筋梗塞 (MI) 群18例の計49例を対象に運動負荷タリウム-201-全身シンチグラフィ (WB-S) を施行し, タリウムの全身分布および動態について検討した. 指標として全身の総カウントに対する各臓器のカウント比 : %distribution (%D) , および各臓器のwashout rate (WR) を算出し検討した. 1) 心臓の%Dは安静時, 負荷時ともに約5%であった. 2) 肺と肝の%Dは負荷時減少し, 大腿と下腿の%Dは負荷時著増した. 3) 臥位負荷法は坐位負荷法に比べて肺の%Dは高く, 大腿の%Dは低い傾向を示した. 4) 心臓のWRはN群に比べAP群MI群とも有意に低下し, 特に多枝病変群, ST低下群でより有意に低下した. 心臓のWRとPRPの間には正相関を認めず, WRには虚血の程度が関与すると思われた. 5) 肺のWRはMI群で有意に高値を示し, 大腿のWRはAP群MI群で有意に低値を示した. |
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| Practice | 臨床医学：一般 |
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| Keywords | Thallium-201 whole body distribution, Whole body imaging, Ischemic heart disease, Supine and upright stress test, Washout rate |
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| English |
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| Title | Clinical Evaluation of Exercise Thallium-201 Whole Body Scintigraphy in Ischemic Heart Disease |
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| Authors | Kenzo KANEKO*, Yoshihiko WATANABE*, Takeshi KONDO*, Yoshihisa KATO*, Takuzo KIRIYAMA*, Mitsuru SAKURAI*, Hiroshi KUROKAWA*, Hitoshi HISHIDA*, Yasushi MIZUNO*, Akira TAKEUCHI**, Sukehiko KOGA** |
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| Authors(kana) | |
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| Organization | *Department of Internal Medicine, **Department of Radiology, Fujita-Gakuen University School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 22 |
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| Number | 2 |
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| Page | 209-217 |
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| Year/Month | 1985/2 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] To evaluate whole body distribution and kinetics of Thallium-201 at exercise and redistribution, whole body scintigraphy (WB-S) was performed on 12 normal subjects (N) , 19 patients with angina pectoris (AP) and 18patients with old myocardial infarction (MD. WB-S was obtained using a gamma camera OMEGA 500 and analized by ADAC System IV. We estimated the following parameters from WB-S ; 1) %Distribution (%D) : the ratio of whole body counts to organ counts 2) washout rate (WR) in each organ. %D of the heart in N, AP and MI was similar at rest and exercise. At exercise, %D of the lung and the liver decreased and %D of thighs increased remarkably than at rest. At supine exercise, the lung indicated high %D and thinghs indicated low %D compared with at upright exercise. WR of the heart in AP and MI was significantly lower than in N (p<0.005, p<0.01) and further decreased proportionally to the number of stenotic coronary arteries and related to the ischemic ST depression of exercise ECG. WR of the heart was not correlation with pressure rate product and this finding suggested that WR of the heart was not prescribed by the tolerance of exercise but related to coronary flow at exercise a certain degree. WR of the lung in MI was significantly higher (p<0.025) and WR of thighs in AP and MI was significantly lower (p<0.025, p<0.05) compared with N. |
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| Practice | Clinical medicine |
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| Keywords | Thallium-201 whole body distribution, Whole body imaging, Ischemic heart disease, Supine and upright stress test, Washout rate |
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