| Japanese |
|---|
| Title | 99mTc-PYP心筋シンチグラフィによる心筋梗塞量の評価 - カウント法による定量的評価の試み - |
|---|
| Subtitle | 短報 |
|---|
| Authors | 桐山卓三*, 近藤武*, 渡辺佳彦*, 金子堅三*, 加藤善久*, 桜井充*, 黒川洋*, 菱田仁*, 水野康*, 江尻和隆**, 竹内昭**, 古賀佑彦** |
|---|
| Authors(kana) | |
|---|
| Organization | *藤田学園保健衛生大学内科, **放射線科 |
|---|
| Journal | 核医学 |
|---|
| Volume | 22 |
|---|
| Number | 1 |
|---|
| Page | 75-79 |
|---|
| Year/Month | 1985/1 |
|---|
| Article | 報告 |
|---|
| Publisher | 日本核医学会 |
|---|
| Abstract | 「I. はじめに」心筋梗塞サイズを知ることは治療上, 予後判定上きわめて重要である. 99mTc-ピロリン酸心筋シンチグラフィ (PYPシンチ) は心筋梗塞巣の陽性描画が可能で, 梗塞の存在診断ばかりでなく梗塞サイズの評価にも応用されつつあるが,十分満足できる結果は得られていない.本研究の目的は PYPシンチからカウント法により梗塞サイズをより定量的に評価することにある. 「II. 対象および方法」急性前壁梗塞 (側壁梗塞1例を含む) 10例 (45〜71歳, 平均年齢59.7歳) と急性下壁梗塞(右室梗塞合併例4例を含む) 10例 (45〜75歳, 平均年齢59.2 歳) を対象として, 梗塞発症後3〜5日目 (平均4.6日目) に99mTc-PYP 20 mCiを静注し, 約3時間後, 正, 側, 第1斜位, 第2斜位 (30°, 40°, 60°) の計6方向のPYPシンチを撮像し, このうち心筋梗塞巣と骨組織の重なりが最も少ない正面像においてFig.1に示すごとく梗塞部 (MI-ROI), MI-ROI内の肋骨部 (R1, R2, R3: Rib-ROI within MI-ROI), MI-ROIの肋骨部 (mRib: Rib-ROI without MI-ROI), MI-ROI外の肋間にbackground (BG) のROIを用手的に設定し,それぞれのROI内のカウントとピクセル数を求め以下の3つの指標, (1) 梗塞巣のROI内のピクセル数 (number of pixels within MI-ROI), (2) 梗塞巣のROI内のカウントからBGおよび肋骨のカウントを差し引いて求めた梗塞巣の単位時間あたりのカウント (MI counts/sec), (3) 肋骨の単位ピクセルあたりの平均カウントに対する梗塞巣のカウント (MI counts) の比 (MI counts/mean Rib counts) を算出し, peak CKとの相関関係を検討した. |
|---|
| Practice | 臨床医学：一般 |
|---|
| Keywords | Tc-99m-stannous pyrophosphate (PYP) myocardial scintigraphy, Myocardial infarct size, Count density method, Quantitative assessment |
|---|
| English |
|---|
| Title | Count Density Method for Sizing Myocardial Infarction with Tc-99m-stannous Pyrophosphate Myocardial Scintigraphy |
|---|
| Subtitle | |
|---|
| Authors | Takuzo KIRIYAMA*, Takeshi KONDO*, Yoshihiko WATANABE*, Kenzo KANEKO*, Yosihisa KATO*, Mituru SAKURAI*, Hiroshi KUROKAWA*, Hitoshi HISHIDA*, Yasushi MIZUNO*, Kazutaka EJIRI**, Akira TAKEUCHI**, Sukehiko KOGA** |
|---|
| Authors(kana) | |
|---|
| Organization | *Department of Internal Medicine, **Department of Radiology, Fujita-Gakuen Health University School of Medicine |
|---|
| Journal | The Japanese Journal of nuclear medicine |
|---|
| Volume | 22 |
|---|
| Number | 1 |
|---|
| Page | 75-79 |
|---|
| Year/Month | 1985/1 |
|---|
| Article | Report |
|---|
| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
|---|
| Abstract | [Summary] The purpose of this report is to evaluate the myocardial infarct size quantitatively with Tc-99m-stannous pyrophosphate (PYP) myocardial scintigraphy using count density method. PYP scintigraphy in anterior projection was recorded in a computer (ADAC system IV) in 20 patients (pts) with anterior and inferior myocardial infarction (MI) within three to five days after onset of symptoms. Region of interests (ROIs) were drawn over the infarct area, ribs and background by visual inspection. Counts and number of pixels within those ROIs were obtained, then MI counts were calculated by subtraction the background and ribs counts from total counts within MI-ROI. The number of pixels within MI-ROI was significantly correlated with peak CK in pts with anterior MI (r=0.79, p<0.01), but it is not in inferior MI. The MI counts/sec, that was normalized by recording time of PYP scintigram, was not correlated with peak CK in both pts with anterior and inferior MI, respectively. On the other hand, the MI counts/mean rib counts was significantly correlated with peak CK in both pts with anterior (r=0.98, p<0.001) and inferior MI (r=0.86, p<0.01), respectively. In conclusion, the count density method (MI counts/mean rib counts) was useful for estimating infarct size in pts with inferior MI as well as anterior MI. |
|---|
| Practice | Clinical medicine |
|---|
| Keywords | Tc-99m-stannous pyrophosphate (PYP) myocardial scintigraphy, Myocardial infarct size, Count density method, Quantitative assessment |
|---|