Japanese
TitleIschemic CardiomyopathyとIdiopathic Dilated Cardiomyopathyの鑑別 - 核医学Imagingの有用性の検討 -
Subtitle原著
Authors栗原正*, 成田充啓*, 村野謙一*, 宇佐美暢久*, 金尾啓右**, 本田稔**
Authors(kana)
Organization*住友病院内科, **RI室
Journal核医学
Volume22
Number1
Page49-55
Year/Month1985/1
Article原著
Publisher日本核医学会
Abstract「要旨」特発性拡張型心筋症 (Idiopathic DCM) 8例, 虚血性心筋症 (Ischemic DCM) 7例に, 201Tl心筋シンチグラフィー, 99mTc心プールイメージングを行い, 両疾患の鑑別における, これら検査法の有用性を検討した. 左室駆出率 (LVEF) は, 安静時には両疾患同等であり (Idiopathic DCM 26.0±13.4%, Ischemic DCM 20.7±9.0%, ns), 運動時のLVEFの減少は, Idiopathic DCM 5例中2例, Ischemic DCM 6例中3例と, 運動時の左心機能の反応に差をみなかった. 心筋シンチでは, 安静時にIschemic DCMでdefectは大きく (defect score: 49.6±5.7 vs. 21.1±13.2%, P<0.001), また, Ischemic DCMでは, 全例で, 冠動脈支配領域に一致したdefectの分布を示したのに対し, Idiopathic DCMでは, 心尖部, 心室基部に散在性のdefectがみられた. 両群ともに, 運動時にdefect scoreの増加はみられなかった. 両疾患の鑑別には, 安静時心筋シンチのdefectのpattern, 大きさが, 運動負荷によるdefectの変化や, 心機能変化より有用と考えられた.
Practice臨床医学:一般
KeywordsIschemic cardiomyopathy, Idiopathic dilated cardiomyopathy, Thallium scanning, Gated cardiac blood pool imaging
English
TitleDifferentiation of Ischemic Cardiomyopathy from Idiopathic Dilated Cardiomyopathy - Evaluation of the Value of Radionuclide Imaging -
SubtitleOriginal Articles
AuthorsTadashi KURIHARA*, Michihiro NARITA*, Kenichi MURANO*, Masahisa USAMI*, Minoru HONDA**, Keisuke KANAO**
Authors(kana)
Organization*Department of Internal Medicine, **Division of Radioisotope, Sumitomo Hospital
JournalThe Japanese Journal of nuclear medicine
Volume22
Number1
Page49-55
Year/Month1985/1
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] To determine whether ischemic cardiomyopathy (ischemic DCM) could be distinguished from idiopathic dilated cardiomyopathy (idiopathic DCM) by radionuclide cardiac imaging, seven patients with ischemic DCM and eight patients with idiopathic DCM were studied with thallium scanning and gated cardiac blood pool imaging at rest and during exercise. The resting ejection fraction of the two groups were similar (ischemic DCM 20.7+-9.0%, idiopathic DCM 26.0+-13.4%, ns), and the change in the ejection fraction during exercise were also similar. Both groups showed no increment of ejection fraction during exercise. Thallium scan showed perfusion defect in 14 of 15 patients. The perfusion defects were extensive in ischemic DCM than idiopathic DCM (defect score 49.6+-5.7 vs. 21.1+-13.2%, P<0.001). Moreover, the distribution of the defects were different; in ischemic DCM the defects were distributed according to the territory of coronary arteries, but in idiopathic DCM, defects were seen frequently in the apex or at the base of left ventricle. In conclusion, resting thallium scan was most reliable imaging technique to distinguish ischemic DCM from idiopathic DCM.
PracticeClinical medicine
KeywordsIschemic cardiomyopathy, Idiopathic dilated cardiomyopathy, Thallium scanning, Gated cardiac blood pool imaging

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