| Japanese |
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| Title | 冠動脈病変の重症度評価における運動負荷Thallium-201心筋像の定量解析の臨床的意義 |
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| Subtitle | 短報 |
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| Authors | 河合直樹*, 松島英夫*, 山本秀平*, 岡田充弘*, 志貴一仁*, 外畑巖*, 小幡康範**, 佐久間貞行**, 都田裕之***, 鈴木晃夫*** |
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| Authors(kana) | |
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| Organization | *名古屋大学医学部第一内科, **放射線科, ***国立名古屋病院循環器科 |
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| Journal | 核医学 |
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| Volume | 21 |
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| Number | 12 |
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| Page | 1621-1626 |
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| Year/Month | 1984/12 |
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| Article | 報告 |
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| Publisher | 日本核医学会 |
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| Abstract | 「I. はじめに」運動負荷Tl心筋像による冠動脈病変の重症度の評価法として, 従来のTl灌流欠損の拡がりの評価の他に, 最近では左室心筋全体におけるTl washout rateあるいは運動直後の肺のTl摂取などの評価が用いられるようになった. しかしこれら定量諸指標間の相関および冠動脈血行再建術前後の定量諸指標の変化についての検討は必ずしも十分には行われていない. 本研究では運動負荷Tl心筋像の定量諸指標について, 冠動脈病変の重症度と比較, 冠動脈血行再建術前後の変化および各指標間の相関を検討することによりこれらの定量諸指標の臨床的意義を検討することを目的とした. 「II. 対象および方法」「1. 対象」心筋梗塞の既往を有しない労作狭心症53名 (男45名, 女8名, 平均52歳), 正常対照11名 (男8名, 女3名, 平均47歳) を対象とし, 冠動脈血行再建術前後の検討にはこの労作狭心症群のうち同手術を受けた4名 (全例男, 平均49歳) の他に陳旧性梗塞を合併した労作狭心症5名 (全例男, 平均48歳) を対象に加えた. |
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| Practice | 臨床医学：一般 |
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| Keywords | Exercise thallium-201 myocardial imaging, Quantitative analysis, Tl washout rate, Angina pectoris, Aortocoronary bypass surgery |
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| English |
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| Title | Noninvasive Assessment of Severity of Coronary Artery Disease by Quantitative Analysis of Exercise Thallium-201 Myocardial Perfusion Imaging |
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| Subtitle | Short Communication |
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| Authors | Naoki KAWAI*, Hideo MATSUSHIMA*, Shuhei YAMAMOTO*, Mitsuhiro OKADA*, Kazuhito SHIKI*, Iwao SOTOBATA*, Yasunori OBATA**, Sadayuki SAKUMA**, Hiroyuki MIYAKODA***, Akio SUZUKI*** |
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| Authors(kana) | |
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| Organization | *First Department of Internal Medicine, Nagoya University School of Medicine, **Department of Radiology, Nagoya University School of Medicine, ***Department of Internal Medicine, Nagoya National Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 21 |
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| Number | 12 |
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| Page | 1621-1626 |
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| Year/Month | 1984/12 |
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| Article | Report |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] A clinical usefulness of quantitative analysis of exercise thallium-201 (Tl) myocardial perfusion imaging in diagnosing the severity of coronary artery disease was evaluated. The materials consisted of 53 effort angina patients without old myocardial infarction (OMI) and 11 normal controls. Additional 5 effort angina patients with OMI were selected for the study before and after aorto-coronary bypass surgery. Exercise and 3-hour redistribution images were obtained in the anterior, the 3 left anterior oblique and the left lateral projections. Three quantitative parameters, percent Tl defect and lung Tl index in the initial images, and mean Tl washout rate (WR) in the left ventricular wall were calculated. The reproducibility of these parameters was good (r = 0.88〜0.98), and their normal ranges were determined. No significant difference in percent Tl defect was shown among single, double and triple vessel disease. In the contrary, the mean WR was significantly lower and lung Tl index was significantly higher in multi-vessel than in single vessel disease. In 9 patients who underwent A-C bypass surgery, the three parameters were either normalized or became less abnormal postoperatively. A significant correlation was shown between mean WR and lung Tl index (r = -0.68, p<0.001). There was a less significant correlation between percent Tl defect and mean WR (r = -0.31 p<0.05), and no significant correlation between percent Tl defect and lung Tl index. It was concluded that the quantitative evaluation of mean washout rate or lung Tl index was important in diagnosing the severity of coronary artery disease with exercise Tl myocardial imaging. |
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| Practice | Clinical medicine |
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| Keywords | Exercise thallium-201 myocardial imaging, Quantitative analysis, Tl washout rate, Angina pectoris, Aortocoronary bypass surgery |
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