| Japanese |
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| Title | N-Isopropyl-P-[123I] Iodoamphetamineによる脳血流像 - 左右差の検出について - |
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| Subtitle | 原著 |
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| Authors | 松田博史*, 関宏恭*, 石田博子*, 隅屋寿*, 横山邦彦*, 久田欣一*, 藤井博之**, 早瀬秀男**, 山本信二郎**, 古林秀則***, 林実*** |
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| Authors(kana) | |
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| Organization | *金沢大学医学部核医学科, **脳神経外科, ***福井医科大学脳神経外科 |
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| Journal | 核医学 |
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| Volume | 21 |
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| Number | 12 |
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| Page | 1587-1596 |
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| Year/Month | 1984/12 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」N-Isopropyl-P-[123I]Iodoamphetamineとガンマカメラ回転型ECT装置を用いて得られた脳血流像において, 左右差指数 (Laterality Index : LI) を算出し, またその画像を作製することにより左右差の客観的評価を試みた. 左右半球でそれぞれすべての矢状断像を加えることにより左側面像 (L) および右側面像 (R) を作製し, 次式によりLIを算出した. LI=100 (1+R-L/R+L). 正常人5例より求めた全脳平均およびピクセルごとのLIの正常範囲 (平均±2標準偏差) は, それぞれ103±4, 103±10となった. 脳血管障害 22例に計25回, 全脳平均およびピクセルごとのLIを求めたところ, それぞれ5回 (20%) ならびに21回 (84%) に異常値および異常値を示す領域が認められた. 一方, X線CTで低吸収域がみられたのは12回 (48%) にすぎなかった. 本法は脳血流像における左右差の評価法として臨床的に有用と考えられる. |
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| Practice | 臨床医学：一般 |
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| Keywords | N-Isopropyl-p-[123I] Iodoamphetamine, Brain perfusion image, Single photon emission computed tomography |
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| English |
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| Title | Brain Perfusion image Using N-Isopropyl-p-[123I] Iodoamphetamine - Detection of interhemispheric Difference - |
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| Subtitle | Original Articles |
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| Authors | Hiroshi MATSUDA*, Hiroyasu SEKI*, Hiroko ISHIDA*, Hisashi SUMIYA*, Kunihiko YOKOYAMA*, Kinichi HISADA*, Hiroyuki FUJII**, Hideo HAYASE**, Shinjiro YAMAMOTO**, Hidenori KOBAYASHI***, Minoru HAYASHI*** |
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| Authors(kana) | |
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| Organization | *Department of Nuclear Medicine, **Department of Neurosurgery, School of Medicine, Kanazawa University, ***Department of Neurosurgery, Fukui Medical College |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 21 |
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| Number | 12 |
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| Page | 1587-1596 |
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| Year/Month | 1984/12 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] In brain perfusion images using N-Isopropyl-p-[123I] Iodoamphetamine and rotating gamma camera emission computed tomography, brain maps showing laterality indices (LI) were made for the purpose of detecting ineterhemispheric differences. Left (L) and right (R) leteral images were made by adding sagittal section images in each hemisphere, respectively. LI was calculated as follows. LI = 100 (1 + R-L/R+L). The normal ranges (mean +- 2 s.d.) of the indices determined by those obtained in five normal right-handed subjects were 103+-4 and 103+-10 for brain mean and each pixel, respectively. Out of 25 measurements in 22 right-handed patients with cerebrovascular accidents, brain mean LI beyond the normal limits and areas showing abnormal regional LI were observed in 5 (20%) and 21 (84%) measurements, respectively. On the other hand, X-ray CT showed low density areas in only 12 (48%). These brain maps were clinically useful for detecting and quantifying interhemispheric differences in brain perfusion images with N-Isopropyl-p-[123I] Iodoamphetamine. |
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| Practice | Clinical medicine |
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| Keywords | N-Isopropyl-p-[123I] Iodoamphetamine, Brain perfusion image, Single photon emission computed tomography |
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