Japanese
Title肝腫瘤検出における肝Single Photon Emission Computed Tomography (SPECT) に関する研究
Subtitle原著
Authors一矢有一*
Authors(kana)
Organization*九州大学医学部放射線科学教室
Journal核医学
Volume21
Number11
Page1445-1461
Year/Month1984/11
Article原著
Publisher日本核医学会
Abstract「要旨」回転型ガンマカメラ方式のSPECT装置を用いて, 肝腫瘍検出における肝SPECTの意義について検討した. 基礎的検討では, 本装置の基本特性について検討するとともに, 肝SPECTの至適撮像条件を設定した. 臨床的検討では371例を対象として, planar imageのみとそれにSPECTを加えた場合とでの腫瘍検出能を比較した. その結果, SPECTを加えた場合の方がsensitivity, specificityともに有意に高く, SPECTの有用性が認められた. しかしながら, SPECTを加えることにより情報が追加できた症例は47例 (12.7%) にしかすぎず, SPECTの有用例は限られたものであった. SPECTが有用であった症例の大部分は, Planar imageで判定に迷う症例と, 肝硬変症例とに含まれていた. SPECTの適応をこれらの症例に限れば, 効率よい検査が可能となる. 逆に, 肝硬変症を除く非腫瘍例ではSPECTの有用性は認められなかった.
Practice臨床医学:一般
KeywordsSPECT, Liver scintigraphy, Liver tumor
English
TitleEvaluation of Single Photon Emission Computed Tomography for Detecting Liver Tumors
SubtitleOriginal Articles
AuthorsYuichi ICHIYA
Authors(kana)
OrganizationDepartment of Radiology, Faculty of Medicine, Kyushu University
JournalThe Japanese Journal of nuclear medicine
Volume21
Number11
Page1445-1461
Year/Month1984/11
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] The advantages of single photon emission computed tomography (SPECT) for detecting liver tumors were estimated using a rotating gamma camera device (Shimadzu LFOV-E). The physical property of the SPECT device and suitable condition for data acquisition were examined. Three hundred and seventy-one patients (160 with liver tumors, 211 without liver tumors) were included in the study. Both conventional liver scintigraphy (planar image) and SPECT with 5 mCi of 99mTc-phytate were performed for each patient. Scintigraphic diagnosis with planar images alone and that in combination with SPECT images were retrospectively compared. Results were as follows: 1. Sensitivity and specificity of planar images alone were 85.0% and 89.4%, respectively. Values with a combination of SPECT images were 89.4% and 93.8%. Combined with SPECT images, there was an improvement in both sensitivity and specificity, and SPECT proved to be a useful modality for detection of liver tumors. 2. However, there were only 47 cases (12.7%), in which the scintigraphic diagnosis was altered by a combination of SPECT images. 3. The majority for whom SPECT altered the diagnosis were included among the cases with equivocal findings on planar images and with liver cirrhosis. 4. Regarding to tumor size and location, SPECT was useful to detect relatively small lesions, centrally located lesions and lesions in the hepatic hilum. 5. SPECT was not useful in those without liver tumors, except for patients with liver cirrhosis. In conclusion, SPECT studies are not deemed necessary for all cases, and this modality should be limited to cases with equivocal findings on planar images and for those with liver cirrhosis.
PracticeClinical medicine
KeywordsSPECT, Liver scintigraphy, Liver tumor

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