Japanese
Title急性心筋梗塞症における発症後の経過と左室駆出率の変動 : RI法による検討
Subtitle原著
Authors中島義治*,†, 南地克美**, 紀田利**, 岡田敏男**, 山田重信**, 後藤武**, 前田和美***, 吉田浩**, 福崎恒*
Authors(kana)
Organization*神戸大学医学部第一内科, †現:琉球大学医学部第三内科, **兵庫県立姫路循環器病センター, ***神戸大学医療技術短期大学部
Journal核医学
Volume21
Number11
Page1437-1443
Year/Month1984/11
Article原著
Publisher日本核医学会
Abstract「要旨」急性心筋梗塞症19例を対象に発症後平均6.4日の急性期と1か月目の慢性期に心プールシンチグラフィを施行し, 左室駆出率 (LVEF) と左室容積の指標を測定し, それらの変化について検討を行った. 前壁梗塞10例の急性期平均LVEFは31±7%と下壁梗塞の54±9% (mean±S.D.) より有意に低く (P<0.001), 慢性期には両者とも増加傾向を示した (前壁梗塞37±8%, 下壁梗塞57±10%). 前壁梗塞10例中4例は平均LVEF 28±6%から43±5%へと有意な増加を示し (改善群, p<0.02), 6例は変化を示さなかった (32±8%→33±7%). 改善群は梗塞領域の壁運動の増加と左室容積の縮小を示し, この群ではcollateralが認められ, collateralが梗塞周辺部の虚血心筋に改善効果をもたらす機序が推測された. 以上の結果から, 急性心筋梗塞症の左室機能は梗塞部位による差異がみられるが, さらに発症後の経過により変化するものと結論した.
Practice臨床医学:一般
KeywordsLeft ventricular ejection fraction, Acute myocardial infarction, Gated blood pool scintigraphy
English
TitleAssessment of Left Ventricular Ejection Fraction by Gated Blood Pool Scintigraphy on Early and Late Phase from the Onset of Acute Myocardial Infarction
SubtitleOriginal Articles
AuthorsYoshiharu NAKASHIMA*, Katsumi MINAMIJI**, Toru KIDA**, Toshio OKADA**, Shigenobu YAMADA**, Takeshi GOTO**, Kazumi MAEDA***, Yutaka YOSHIDA**, Hisashi FUKUZAKI*
Authors(kana)
Organization*First Department of Internal Medicine, Kobe University, **Hyogo Brain and Heart Center at Himeji, ***School of Allied Medical Science, Kobe University
JournalThe Japanese Journal of nuclear medicine
Volume21
Number11
Page1437-1443
Year/Month1984/11
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] To evaluate the change of left ventricular function after the onset of acute myocardial infarction, gated blood pool scintigraphy was performed in 19 patients on early and late phase (6 days and 1 month on the average). There was a difference in left ventricular ejection fraction (LVEF) between patients with anterior and inferior myocardial infarction. Patients with anterior infarction indicated low value of LVEF (31+-7%) on acute phase and its value was increased on chronic phase (37+-8%), whereas patients with inferior infarction had higher value of LVEF not only on acute phase but also on chronic phase (54+-9%→57+-10%), than those with anterior infarction. Left ventricular volume was larger in anterior group than in inferior group and tended to become smaller on chronic phase. In 4 of 10 cases with anterior infarction, a significant improvement of LVEF was found from 28+-6% to 43+-5%, but in 6 cases LVEF was unchanged during the same period. In 3 cases out of improved group, it was demonstrated angiographically that the collateral vessels were developed. It was, thus, suggested that collateral vessels may play an important role in the recovery of myocardial ischemia and wall motion abnormality in the marginal zone of infarcted area. From these results, we concluded that left ventricular function changed serially in most patients from the early phase to the late phase after the onset of acute myocardial infarction.
PracticeClinical medicine
KeywordsLeft ventricular ejection fraction, Acute myocardial infarction, Gated blood pool scintigraphy

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