Japanese
Title甲状腺機能亢進症のNa 131I治療における追跡症例の検討
Subtitle原著
Authors筧弘毅*, 古川隆*, 深草駿一*, 太中弘**, 高橋有二**
Authors(kana)
Organization*日本赤十字社医療センター放射線科, **外科
Journal核医学
Volume21
Number10
Page1293-1299
Year/Month1984/10
Article原著
Publisher日本核医学会
Abstract「要旨」Na 131I治療を行った甲状腺機能亢進症(バセドウ病)41症例につき追跡調査の結果を検討する. 対象症例は男10名, 女31名で, 男女比は1:3.1である. 治療時の年齢は20〜60歳台で, 40歳台が男女ともに最多である. 経過観察期間は1〜3年で, 5年以上が51%, 2年以上が83%である. Na 131I治療回数は1回が37例(90%), 2回2例, 3年間に4回1例, 6年間に5回1例である. 甲状腺吸収線量は治療量投与時の実測値より計算し, 4,000〜6,000rad(40〜60Gy)とした. 6,000radでは機能低下症が多く現れる傾向があり, 4,000〜5,000radでは機能亢進症が多く残る傾向がある. 結論としては4,000〜5,000radを目標として治療を行うか, 3〜6mCi程度を投与し, 効果が不十分の場合にはNa 131I治療を繰り返し行うか, 抗甲状腺剤を投与する. 昭和58年10月現在の成績としては, 41症例中正常25例(61.0%), 機能亢進症12例(29.2%), 機能低下症4例(9.8%)である.
Practice臨床医学：一般
KeywordsHyperthyroidism, Na 131I therapy.
English
TitleTherapy of Hyperthyroidism with Na 131I
SubtitleOriginal Articles
AuthorsHirotake KAKEHI*, Takashi FURUKAWA*, Shunichi FUKAKUSA*, Hiroshi FUTONAKA**, Yuji TAKAHASHI**
Authors(kana)
Organization*Department of Radiology, **Department of Surgery, The Japanese Red Cross Medical Center
JournalThe Japanese Journal of nuclear medicine
Volume21
Number10
Page1293-1299
Year/Month1984/10
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary]Forty one patients of hyperthyroidism were treated with Na 131I. Men and women are in the ratio 1:3.1. The ages of patients are between twenties and sixties and the forties are the highest in number. The observation period of clinical courses is between 1 and 8 years. The number of patients observed over 5 years are 51% of them and over 2 years are 83%. The treatment frequency is as follows: On 37 cases each one was treated once with Na 131I. 2 cases twice, 1 case at 4 times in 3 years and 1 case at 5 times in 6 years. The treatment doses are between 4,000-6,000 rad (40-60 Gray). In the cases treated with the irradiation dose of 6,000 rad, we often saw hypothyroidism. In cases aiming 4,000-5,000 rad, there is a tendency of leaving hyperthyroidism unrecovered. In conclusion, the patients should be treated giving 4,000-5,000 rad or with Na 131I doses of 3-6 mCi. If the effects of the treatment are insufficient, the patients should be further treated with anti-thyroid drug or treated again with Na 131I. As the result, there are at present 25 cases (61.0%) in normal status of the thyroid gland, 12 cases (29.2%) in hyperthyroidism and 4 cases (9.8%) in hypothyroidism totaling 41 cases in all.
PracticeClinical medicine
KeywordsHyperthyroidism, Na 131I therapy.

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