| Japanese |
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| Title | 201Tl心筋single photon emission computed tomographyによる拡張型心筋症の検討 - 形態的および定量的評価 - |
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| Subtitle | 原著 |
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| Authors | 二神康夫*, 牧野克俊*, 市川毅彦*, 小西得司*, 浜田正行*, 中野赳*, 竹沢英郎*, 伊藤綱朖**, 前田寿登**, 李学中*** |
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| Authors(kana) | |
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| Organization | *三重大学医学部第一内科, **放射線科, ***中国・白求恩医科大学内科 |
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| Journal | 核医学 |
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| Volume | 21 |
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| Number | 8 |
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| Page | 909-919 |
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| Year/Month | 1984/8 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」201Tl心筋SPECTを用い拡張型心筋症(DCM:n=14)を形態的および定量的に評価した. 安静時画像を用い, 定量評価はファントム実験を基に行った. 結果:[I]形態評価:球状の著明な内腔拡大(14/14), 限局性あるいはびまん性の集積低下〜欠損(12/14), 右室壁の描出(6/14)が特徴所見であり, 虚血性心疾患との鑑別では, 欠損の程度に不釣り合いな内腔拡大所見により比較的容易(13/14)であった. [II]定量評価:DCMでは正常例(n=5)と比べ(1)左室心筋201Tl摂取率(4.8±1.3%:3.3±0.2%, P<0.01)および有効左室心筋量(255±54.1ml:141.6±22.4ml, p<0.001)が有意に高値であった. (2)単位体積当たりの201Tl摂取率[(18.9±4.3)×10-5:(23.6±3.8)×10-5, p<0.05]は有意に低値であった. (3)心筋/肺・平均カウント比は有意に低値であった. 以上安静時201Tl心筋SPECTを用い, DCMと虚血性心疾患の鑑別が可能であり, さらに定量評価は形態評価の客観的裏づけともなり, 臨床応用可能と考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | Dilated cardiomyopathy, 201Tl myocardial SPECT, Left ventricular mass, 201Tl myocardial uptake ratio. |
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| English |
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| Title | Evaluation of Dilated Cardiomyopathy by 201Tl Myocardial Single Photon Emission Computed Tomography - Morphological and Quantitative Analysis - |
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| Subtitle | Original Articles |
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| Authors | Yasuo FUTAGAMI*, Katsutoshi MAKINO*, Takehiko ICHIKAWA*, Tokuji KONISHI*, Masayuki HAMADA*, Takeshi NAKANO*, Hideo TAKAZAWA*, Tsunao ITO**, Hisato MAEDA**, Li XUEZHONG*** |
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| Authors(kana) | |
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| Organization | *First Department of Internal Medicine, **Department of Radiology Mie University School of Medicine, ***Department of Internal Medicine, Bai Chu En Medical School |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 21 |
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| Number | 8 |
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| Page | 909-919 |
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| Year/Month | 1984/8 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary]To estimate dilated cardiomyopathy (DCM) morphologically and quantitatively, 201Tl myocardial single photon emission computed tomography (SPECT) was performed in 14 DCM and 5 normal cases. Using a rotating dual-gamma camera system, resting SPECT data were collected for 6 minutes. Quantitative analysis of clinical cases was based on phantom studies. (I) Morphological features Marked spherical left ventricular (LV) dilatation (14/14), localized-diffuse low uptake or defect (12/14), and right ventricular visualization (6/14) were characteristic features in DCM. Differentiation of DCM from ischemic heart disease by SPECT was possible through the feature indicating disproportionately large LV cavity to defect size or degree. (II) Quantitative analysis When DCM was compared with normal control (n-5), following 3 features were impressive; 1) DCM was significantly higher in LV myocardial 201Tl uptake ratio and LV volume than normal control. (4.8 +- 1.3%: 3.3 +- 0.2%, p<0.01, 255.5 +- 54.1 ml: 141.6 +- 22.4 ml, p<0.001, respectively) 2) DCM was significantly lower in LV myocardial 201Tl uptake ratio of unit volume (1 ml) than normal control. 3) DCM was significantly lower in mean myocardial count/mean lung count・ratio than normal control. Thus we concluded that 201Tl myocardial SPECT was useful non-invasive technique for diagnosis of DCM and was with fairly well correlation between morphology and quantitative estimations. Furthermore, this quantitative method appears to be applicable for estimation of other cardiac disease. |
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| Practice | Clinical medicine |
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| Keywords | Dilated cardiomyopathy, 201Tl myocardial SPECT, Left ventricular mass, 201Tl myocardial uptake ratio. |
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