Japanese
TitleArm Counterを用いた47Ca吸収テストの臨床的検討
Subtitle原著
Authors戎野庄一*, 森本鎮義*, 鳥住和民**, 山田龍作**,****, 太田喜一郎***, 大川順正*,****
Authors(kana)
Organization*和歌山県立医科大学泌尿器科学教室, **放射線科学教室, ***高年病内科学教室, ****主任:教授
Journal核医学
Volume21
Number8
Page901-907
Year/Month1984/8
Article原著
Publisher日本核医学会
Abstract「要旨」Scintiscannerをarm counterとして改良し, 47Ca吸収テストを2〜3のCa代謝異常をきたす疾患に試み, その結果の検討ならびに本検査法の臨床的意義などにつき記載した. 壮年期の健常男子では平均54.1%の47Ca吸収率を示し, 他方, 女子のそれは51.3%であり, 壮年期の男女間には腸管でのCa吸収には差異がみられなかった. 原発性副甲状腺機能亢進症の患者では異常高値が示され, 副甲状腺機能低下症では著しい低値がみられた. また, 女子の骨粗鬆症患者においても47Ca吸収率の低下がみられた. 尿路結石症においては, 過Ca尿症を伴う患者に高吸収率を示すものがあり, 過Ca尿症の病因の鑑別, すなわち腸管吸収型あるいは腎漏出型かの検索がこれによって可能となり得る. さらに腸管型の過Ca尿症に対する治療前後の結果では, 本検査が尿路結石症の再発予防効果の判定に役立つものであることを示し, 副甲状腺手術前後の検査においては, その治療効果の判定が可能であることを示した. 本法はきわめて簡便で, どこの施設においてもおこなうことが可能であるところから, Ca代謝異常をきたす疾患のroutine検査の一つとなり得るものと考えられる.
Practice臨床医学:一般
Keywords47Ca absorption test, Hyperparathyroidism, Hypoparathyroidism, Osteoporosis, Urolithiasis.
English
TitleClinical Studies of Intestinal 47Ca Absorption Test by External Arm Counter
SubtitleOriginal Articles
AuthorsShoichi EBISUNO*, Shigeyoshi MORIMOTO*, Kazutami TORIZUMI**, Ryusaku YAMADA**, Kiichiro OHTA***, Tadashi OHKAWA*
Authors(kana)
Organization*The Departments of Urology, **Radiology, ***Gerontology, Wakayama Medical Collage
JournalThe Japanese Journal of nuclear medicine
Volume21
Number8
Page901-907
Year/Month1984/8
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary]An arm counter used to measure fractional accumulation of 47Ca on the forearm following an intravenous and a later oral dose of the radioisotope, and the intestinal 47Ca absorption rate was calculated. Clinical studies were carried out in normal subjects and patients with some disorders of calcium metabolism, using this external counting techinique. The following results were obtained; (1) In 12 healthy control men (mean age 31.8y), calcium absorption rate ranged from 42.5% to 59.6% (mean +- SD; 54.1 +- 4.7%). In 6 healthy women (mean age 31.4y), the rate ranged from 46.8% to 57.3% (mean +- SD; 51.3 +- 4.3%). The intestinal calcium absorption was not related to the sex in younger adult. (2) The fractional absorption of calcium were significantly increased in patients with primary hyperparathyroidism, whereas reduced in hypoparathyroidism. (3) In 5 female subjects affected by osteoporosis, a defective intestinal absorption of calcium was observed. (4) The calcium absorption tests were carried out on normo- and hypercalciuric patients with calcium urolithiasis. Higher absorption of calcium was recognized in some hypercalciuric patients. (5) In hypercalciuric calcium stone formers with rice-bran treatment, 47Ca absorption from gut were decreased significantly. (6) This method is very convenient to determine the intestinal absorption of 47Ca, When a protective covering of lead is prepared for scinti-scanner, the 47Ca absorption test can be done for the patients with calcium metabolic disorder on a routine examination.
PracticeClinical medicine
Keywords47Ca absorption test, Hyperparathyroidism, Hypoparathyroidism, Osteoporosis, Urolithiasis.

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