| Japanese |
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| Title | 13NH3による心筋ポジトロンCTイメージングの心筋梗塞診断への応用 - Positologica-IIによる経時的イメージと多断層イメージ - |
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| Subtitle | 原著 |
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| Authors | 宍戸文男*, 舘野之男*, 吉田勝哉**, 池平博夫*, 山根昭子*, 福田信男*, 山崎統四郎*, 鈴木和年***, 玉手和彦***, 中山隆***, 入江俊章*, 福士清*, 井上修*, 増田善昭** |
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| Authors(kana) | |
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| Organization | *放射線医学総合研究所臨床研究部, **千葉大学医学部第三内科, ***放射線医学総合研究所サイクロトロン管理課 |
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| Journal | 核医学 |
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| Volume | 21 |
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| Number | 7 |
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| Page | 799-804 |
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| Year/Month | 1984/7 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」局所心筋血流量を指示するトレーサと考えられている13NH3と全身用多断層ポジトロンCTであるポジトロジカ-IIを用いて13NH3ボーラス注入後の心筋の経時的イメージングと平衡時の多断層イメージングを合わせて行った. 経時的イメージングでは1回のトレーサの注入で心内腔のイメージと心筋のイメージとが得られる. この位相の異なるふたつのイメージを比較したり, 心内腔の輪郭を抽出して心筋イメージに重ねて表現することにより心内腔と心筋との関係が明瞭となり, 心筋梗塞の部位と大きさの確認, および心室瘤の診断に役立つこと, 6mm間隔の多断層イメージでは心筋の血流低下の部位や範囲がより明瞭となることより, 本法は心筋梗塞の診断に有用な情報を与える方法と考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | 13NH3, positron CT, myocardial infarction, myocardial blood flow. |
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| English |
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| Title | Positron CT Imaging for Assessment of Myocardial Infarction with 13NH3 : Its Usefulness of Dynamic Images and Multi-plane Images |
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| Subtitle | Original Articles |
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| Authors | Fumio SHISHIDO*, Yukio TATENO*, Katsuya YOSHIDA**, Hiroo IKEHIRA*, Teruko YAMANE*, Nobuo FUKUDA*, Toshiro YAMASAKI*, Kazutoshi SUZUKI***, Kazuhiko TAMATE***, Takashi NAKAYAMA***, Toshiaki IRIE*, Kiyoshi FUKUSHI*, Osamu INOUE*, Yoshiaki MASUDA** |
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| Authors(kana) | |
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| Organization | *Division of Clinical Research, National Institute of Radiological Sciences, **Third Department of Internal Medicine, Chiba University School of Medicine, ***Section of Cyclotron, National Institute of Radiological Sciences |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 21 |
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| Number | 7 |
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| Page | 799-804 |
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| Year/Month | 1984/7 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary]We applied a whole-body multi-slice positron CT device for heart imaging. The positron CT device was POSITOLOGICA-II which had been installed in our institute and radiopharmaceutical was 13NH3. POSITOLOGICA-II consists of 3 continuously rotating circular rings of 160 BGO detectors, providing 5 simultaneous slices. Preliminary measurements of resolution showed 9.2 mm FWHM, and measured sensitivity was 28 and 38 kcps/μCi/ml for in-plane and cross-plane, respectively. Sequential imaging with 60 second-interval scan and 3 additional scans that provided 15 static images of 6 mm interval were performed after 10-20 mCi of 13NH3 by interaveous bolus injection. Three patients with myocardial infarction and two normal cases were examined by this method. The image of the first 60 second-interval showed blood pool image of heart, and the 5th image revealed myocardium. Compared between these two sequential images the endocardial borders were delineated. In a patient with extensive anterior myocardial infarction, the location of ventricular aneurysm were clearly detected. Three additional late scans provided high quality cross sectional images of left myocardium. The images of a patient with myocardial infarction showed the reduced blood flow regions at the sites corresponding to the specific electrocardiographic findings. These preliminary clinical results suggest that sequential tomographic heart imaging using whole-body multi-silce Positron CT device and 13NH3 are useful for assessment of myocardial infarction. |
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| Practice | Clinical medicine |
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| Keywords | 13NH3, positron CT, myocardial infarction, myocardial blood flow. |
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