Japanese
Title心筋梗塞症における運動負荷タリウム心筋像の初期摂取率および再分布の意義について
Subtitle原著
Authors渡辺佳彦*, 殿岡一郎**, 金谷透**, 立木楷**, 安井昭二**, 駒谷昭夫***, 山口昂一***
Authors(kana)
Organization*名古屋保健衛生大学医学部内科, **山形大学医学部第一内科, ***放射線科
Journal核医学
Volume21
Number4
Page319-330
Year/Month1984/4
Article原著
Publisher日本核医学会
Abstract「要旨」陳旧性心筋梗塞症 (MI) 29例および労作性狭心症 (AP) 29例を対象として, トレッドミル運動負荷201Tl心筋シンチグラフィを施行し, その201Tl動態を経時的に観察し検討した. 201Tl 2mCiを負荷終了1分前に投与し, 直後像および3時間後の遅延像を4方向にて撮像した. 心筋を6分節に分割し, 各部位の初期摂取率 (IU) , およびredistribution index (RDI, 最大washout rateに対する各部位のwashout rateの比率) を指標とし, 冠動脈および左室造影所見と対比検討した. MIでは, 壁運動異常が高度なほどIU, RDIは低値であった. また冠動脈狭窄度が高度なほどIU, RDIは低値であった. 一方, APでは冠動脈狭窄度が大なるに伴いIUは低下したが, RDIは増加を示した. 以上の事実は, 201Tlの初期摂取率および再分布には冠狭窄度が強く関与するが, 残存心筋量とも密に関係するためと考えられた.
Practice臨床医学:一般
KeywordsMyocardial perfusion image, Redistribution, Myocardial infarction, Angina pectoris, Ventricular wall motion.
English
TitleEvaluation of Initial Uptake and Redistribution on Stress Thallium-201 Myocardial Perfusion Images in Patients with Myocardial Infarction
SubtitleOriginal Articles
AuthorsYoshihiko WATANABE*, Ichiroh TONOOKA**, Tohru KANAYA**, Kai TSUIKI**, Shouji YASUI***, Akio KOMATANI***, Kouichi YAMAGUCHI***
Authors(kana)
Organization*Department of Internal Medicine, Fujita Gakuen University, **First Department of Internal Medicine, ***Department of Radiology, Yamagata University School of Medicine
JournalThe Japanese Journal of nuclear medicine
Volume21
Number4
Page319-330
Year/Month1984/4
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] Stress thallium-201 myocardial perfusion imaging was performed on 29 patients with previous myocardial infarction and 29 patients with angina pectoris at exercise to evaluate thallium-201 kinetics in ischemic heart disease. Four views of thallium-201 images (right anterior oblique, antero-posterior, left anterior oblique and left lateral views) were obtained at 5 min after treadmill exercise with administration of 2 mCi of thallium-201 chloride (initial image) and at 3 hours later (delayed image) . Myocardial images were divided into 6 segments (anterior, lateral, inferior, posterior, apical and septal segments) and initial uptake (IU) and redistribution index (RDI, the ratio of the maximal washout rate to a washout rate in each segment) were calculated in order to assess the relations of thallium-201 kinetics to wall motion abnormality and coronary artery stenosis. In myocardial infarction, IU and RDI were decreased in proportion to the severity of wall motion abnormality and coronary artery stenosis. Contrarily, in angina pectoris, IU was decreased but RDI was increased proportionally to the severity of coronary arterial stenosis. In conclusion, IU and redistribution of thallium-201 were affected essentially by both the grade of coronary arterial stenosis and the amount of residual viable heart muscle in patients with ischemic myocardial disease.
PracticeClinical medicine
KeywordsMyocardial perfusion image, Redistribution, Myocardial infarction, Angina pectoris, Ventricular wall motion.

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