Japanese
Title多結晶型ガンマカメラによる左室容量曲線の解析
Subtitle原著
Authors千田道雄*, 玉木長良*, 米倉義晴*, 児玉秋生*, 鳥塚莞爾*, 伊藤秀臣**, 才木康彦**, 杤尾人司**, 山口晴二**, 池窪勝治**, 加藤洋***, 吉川純一***
Authors(kana)
Organization*京都大学医学部放射線核医学科, **神戸市立中央市民病院核医学科, ***循環器内科
Journal核医学
Volume21
Number3
Page231-239
Year/Month1984/3
Article原著
Publisher日本核医学会
Abstract「要旨」 多結晶型ガンマカメラを用いて, ファーストパス法による安静時心RIアンギオグラフィーを1フレーム0.02秒で施行した. 数心拍の重ね合わせによって得られた左室容量曲線とその一次微分から, 収縮期および拡張期の種々の指標を算出しその有用性を検討した. 心筋梗塞 (17例) では, 最大駆出速度 (PER) , 収縮早期1/3の駆出率 (1/3 EF) と平均駆出速度 (1/3 ER) , 最大充満速度 (PFR) , および拡張早期1/3の平均充満速度 (1/3 FR) が, いずれも正常群 (6例) に比べ有意に低下した. 狭心症 (10例) では, PFRが正常群に比べて有意に低下した. 心筋梗塞や狭心症のなかに, EFは正常であるにもかかわらずPFRの低下している例がかなり認められた. 多結晶型ガンマカメラは感度が高いので0.02秒毎の撮影が可能で, 収縮期および拡張期の諸指標を算出することができ, 心機能の評価にきわめて有用であると考えられた.
Practice臨床医学：一般
Keywordsmulticrystal gamma camera, time-activity curve, first-pass method, coronary artery disease, diastolic phase index.
English
TitleAnalysis of Left Ventricular Time-activity Curve Obtained from First-pass Radionuclide Angiography with Multicrystal Gamma Camera
Subtitle
AuthorsMichio SENDA*, Nagara TAMAKI*, Yoshiharu YONEKURA*, Shusei KODAMA*, Kanji TORIZUKA*, Hidetomi ITO**, Yasuhiko SAIKI**, Hitoshi TOCHIO**, Haruji YAMAGUCHI**, Katsuji IKEKUBO**, Hiroshi KATO**, Jun'ichi YOSHIKAWA**
Authors(kana)
Organization*Department of Radiology and Nuclear Medicine, Kyoto University Medical School, **Kobe Central Municipal Hospital
JournalThe Japanese Journal of nuclear medicine
Volume21
Number3
Page231-239
Year/Month1984/3
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] First-pass radionuclide angiography was performed at rest with a multicrystal gamma camera in RAO projection at the framing rate of 0.02 sec. LV time-activity curve was obtained by summing several cardiac beats selected from LV phase. No curve fitting was done. From the curve and its first derivative, following indexes of cardiac performance were calculated: EF (Ejection fraction) , PER (Peak ejection rate) , TPE (Time to peak ejection) , PFR (Peak filling rate) , TPF (Time to peak filling) , 1/3EF and 1/3ER (Ejection fraction and Mean ejection rate of first third of systole respectively, normalized by end-diastolic count) , 1/3FF and 1/3FR (Filling fraction and Mean filling rate of first third of diastole respectively, normalized by the count at the end of the first third of diastole) . Patients with myocardial infarction (MI) showed significantly lower PER, 1/3EF, 1/3ER, PFR, 1/3FF and 1/3FR than normal group. Those with angina pectoris had significantly lower PFR than normal. Some patients with angina or MI had normal EF but lower PFR than normal. We conclude that indexes of systolic and diastolic parameters can be assessed using first-pass radionuclide angiography with multicrystal gamma camera and that this method is a useful technique for evaluating cardiac performance.
PracticeClinical medicine
Keywordsmulticrystal gamma camera, time-activity curve, first-pass method, coronary artery disease, diastolic phase index.

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