| Japanese |
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| Title | 急性心筋梗塞症における99mTc-ピロリン酸シンチグラフィの持続集積画像の臨床的意義 |
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| Subtitle | 原著 |
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| Authors | 中島義治*, 福崎恒*, 前田和美**, 南地克美***, 紀田利***, 吉田浩*** |
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| Authors(kana) | |
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| Organization | *神戸大学医学部第一内科, **神戸大学医療技術短期大学, ***兵庫県立姫路循環器病センター |
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| Journal | 核医学 |
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| Volume | 21 |
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| Number | 3 |
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| Page | 221-229 |
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| Year/Month | 1984/3 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」虚血性心疾患73例 [急性心筋梗塞 (AMI) 70例, 不安定狭心症3例] を対象に99mTc-ピロリン酸 (PYP) シンチグラフィーを急性期および慢性期に施行し, 持続集積画像を示す例の臨床成績の検討からその意義を考察した. 急性期AMI症例の90%が, 99mTc-PYP心筋集積像を示し, AMI発症後, 平均37日目の再検にて67% (28/42) で集積像が消失, 33% (14/42) に持続集積画像が認められた. 持続集積画像は急性期の集積状態が限局性高度集積 (localized pattern, marked intensity) から慢性期のびまん性軽度集積 (diffuse pattern, faint intensity) に変化する例が多く, この群に梗塞範囲が大きく (max LDH 3053±958 IU/l, Tl-201 large defect size 10/13例) 高度左心機能障害例 (PADP 18±7mmHg, LVEF 28±11%: mean±SD) を多く認め, 2名が死亡した. 以上より99mTc-PYP持続集積画像は持続する心筋障害をあらわし重症例を示唆する所見と考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | technetium-99m pyrophosphate myocardial scintigram, persistently positive image, acute myocardial infarction. |
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| English |
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| Title | Clinical Significance of Persistently Positive Technetium-99m Pyrophosphate Myocardial Scintigrams in Patients with Acute Myocardial Infarction |
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| Subtitle | |
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| Authors | Yoshiharu NAKASHIMA*, Hisashi FUKUZAKI*, Kazumi MAEDA**, Katsumi MINAMIJI***, Toru KIDA***, Yutaka YOSHIDA*** |
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| Authors(kana) | |
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| Organization | *First Department of Internal Medicine, Kobe University, **School of Allied Medicine Science, Kobe University, ***Hyogo Brain and Heart Center at Himeji |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 21 |
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| Number | 3 |
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| Page | 221-229 |
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| Year/Month | 1984/3 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] To evaluate the clinical significance of persistently positive technetium-99m pyrophosphate (99mTc-PYP) myocardial scintigrams, 99mTc-PYP myocardial scintigrams were obtazined in 73 patients with acute myocardial infarction (AMI) during acute phase and chronic phase (37 days later in an average) . Sixty-three of 70 patients (90%) had a positive scintigram in acute phase. At follow-up scintigraphy, 33% of patients had a persistently positive scintigram and the degree of 99mTc-PYP myocardial uptake was changed from localized pattern with marked intensity to diffuse pattern with faint intensity. Patients with persistently positive scintigrams were demonstrated to have severe myocardial damages as evidenced by large infarct size (max. LDH 3053+-958 IU/l, large size defect with thallium-201 myocardial scintigraphy) and marked left ventricular dysfunction (PADP 18+-7 mmHg, RIEF 28+-11%) . Two patients with persistently positive scintigrams were expired. It is, thus, concluded that a persistently positive 99mTc-PYP myocardial scintigrams indicates the existence of progressive myocardial damage and accordingly this finding is of great use for assessing the prognosis of AMI. |
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| Practice | Clinical medicine |
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| Keywords | technetium-99m pyrophosphate myocardial scintigram, persistently positive image, acute myocardial infarction. |
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