Japanese
Title左室駆出率推定のためのバックグラウンド曲線処理に関する研究
Subtitle短報
Authors鈴木豊*, 中村正彦**, 友田春夫***
Authors(kana)
Organization*東海大学医学部放射線医学教室, **ME学教室, ***循環器内科学教室
Journal核医学
Volume21
Number2
Page149-153
Year/Month1984/2
Article報告
Publisher日本核医学会
Abstract「I. はじめに」 心RIアンジオグラフィ (RCG) から左室駆出率 (LVEF) を算出するにあたって, バックグラウンド曲線 (BKG) の推定はもっとも重要な問題である. しかし, 解析的にBKGを推定する方法は確立されておらず, 経験則が主として用いられている. われわれは, これまで, 初回通過法によって得られる単一の左室時間放射能曲線 (LVTAC) より最小2乗法に基礎をおいた方法でBKGを解析的に推定する方法を提案し, 種々の検討を加えてきた. 今回は, ガンマカメラによって収録したRCG上で大きさの異なる左室関心領域 (ROI) を設定し, そのおのおののLVTACからわれわれの提案した方法でLVEFを求め, 比較検討した結果を報告する. 「II. 解析理論」 初回通過LVTACは次式によって一般的に表わされるものとする.
Practice臨床医学：一般
KeywordsFirst Pass Radionuclide Angiocardiography, Background Estimation, Digital Filtering Technique.
English
TitleAnalytical Approach for Correction of Background Counts in First Pass Left Ventricular Time-Activity Curves
SubtitleShort Communication
AuthorsYutaka SUZUKI*, Masahiko NAKAMURA**, Haruo TOMODA***
Authors(kana)
Organization*Department of Radiology, **Medical Engineering, ***Cardiology, Tokai University Medical School Isehara City
JournalThe Japanese Journal of nuclear medicine
Volume21
Number2
Page149-153
Year/Month1984/2
ArticleReport
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] Left ventricular time-activity curve (LVTAC) is mathematically described by the following equation. A (t1) =KC (t1) (VES+VST V (t1) ) +B (t1) where A (t1) is the observed curve, K is a constant, C (t1) is the tracer concentration in the left ventricle (LV) , VES denotes the end-systolic volume of the LV, VST denotes the stroke volume of the LV, and V (t1) is the volume variation curve of the LV being normalized so as to be zero at end-systole and unity at end-diastole and B (t1) is the background curve. An envelop curve is obtained by applying the technique of complex demodulation to a LVTAC and a low pass filtered curve is also obtained from the LVTAC. A BKG is approximately estimated from these two curves using the least square method. First pass radionuclide angiocardiographies were done in 25 patients with various heart diseases. Three different regions of interest (ROI) were selected as following: ROI-1 covered only LV, ROI-2 covered LV and its surrounding areas in 1 cm wide, and ROI-3 covered both LV and right ventricle simultaneously. The LVTAC at 0.005s intervals of each ROI was generated and its BKG was estimated. In this estimation BKG was assumed to be a polynomial of degree 1 in considered interval. Left ventricular ejection fraction (LVEF) was culculated from each BKG corrected LVTAC. The LVEFs obtained from ROI-2 and ROI-3 were compared with those from ROI-1, respectively. There was a good correlation between the LVEFs from ROI-1 and those from ROI-2: correlation coefficient (r) =0.947, there was also a fairly good correlation between the LVEFs from ROI-I and those from ROI-3: (r) =0.886. These results suggest that BKG is estimated correctly by our technique.
PracticeClinical medicine
KeywordsFirst Pass Radionuclide Angiocardiography, Background Estimation, Digital Filtering Technique.

【全文PDF】