| Japanese |
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| Title | 201TlClの初期および後期シンチグラフィによる甲状腺癌の鑑別診断 |
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| Subtitle | 原著 |
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| Authors | 筧弘毅*, 古川隆*, 深草駿一*, 高橋有二**, 太中弘** |
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| Organization | *日本赤十字社医療センター放射線科, **外科 |
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| Journal | 核医学 |
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| Volume | 21 |
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| Number | 2 |
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| Page | 141-147 |
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| Year/Month | 1984/2 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」結節性甲状腺腫の良否の鑑別の可能性を検討するため, 201TlClによる初期と後期のシンチグラムを撮像し, 甲状腺結節部における201TlCl集積の消長を観察した. 後期シンチグラム上での201TlClの結節部残存 (+) (-) と, 病理組織上での結節の悪性, 良性とを対比し, 正陽性, 偽陰性, 正陰性, 偽陽性の4種類に分類した. 例数はそれぞれ25, 9, 35, 5例, 計74例である. 病理組織上正診された甲状腺癌のsensitivityは73.5%, 良性結節性甲状腺腫のspecificityは87.5%, 検査結果陽性例のPredictive valueは83.3%, 陰性例のpredictive valueは79.5%であった. 甲状腺癌および良性結節性甲状腺腫全体のaccuracy は81.1%である. 上述の結果より, 結節部への201TlClの集積が後期シンチグラム上に残存し, 他部の集積が消失する場合には甲状腺癌を, 後期シンチグラム上の集積像が消えるか, 201TlClが甲状腺全体に残存する時には良性結節性甲状腺腫を疑う. |
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| Practice | 臨床医学：一般 |
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| Keywords | Nodular goiter, 201TlCl scintigraphy, Early and delayed scintigraphy. |
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| English |
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| Title | Differential Diagnosis of the Malignant and Benign Nodular Goiters with 201TlCl Early and Delayed Scintigraphy |
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| Subtitle | Original Articles |
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| Authors | Hirotake KAKEHI*, Takashi FURUKAWA*, Shunichi FUKAKUSA*, Uji TAKAHASHI**, Hiroshi FUTONAKA** |
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| Authors(kana) | |
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| Organization | *Department of Radiology, **Department of Surgery, The Japanese Red Cross Medical Center |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 21 |
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| Number | 2 |
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| Page | 141-147 |
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| Year/Month | 1984/2 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Thallium-201 chloride (201TlCl) has a tendency to be taken up by relatively differentiated tumor cells and has possibility of obtaining a positive scintigraphy of nodular goiters. Also it has a characteristic of remaining longer period in the cells of malignant tumors, comparing with those of benign ones. Utilizing those natures of 201TlCl, the early (5-15 minutes) and delayed (2-4 hours) scintigrams were carried out to differentiate the malignancy of cold nodules on the Na131i scintigraphy. Comparing the remaining and disappearance of the 201TlCl accumulation on the delayed scintigraphy and the malignancy or benignancy of the nodule pathology, 4 types of cases, namely, true positive, false negative, true negative and false positive ones, were classified. Numbers of the each group are 25, 9, 35 and 5 respectively, totaling 74 cases in all. The correct diagnosis of the cases are as follows. The sensitivity of the malignant tumors histologically confirmed is 73.5% and the specificity of the benign tumors is 87.5%. The predictive value of a positive test result is 83.3% and that of a negative test result is 79.5%. The total accuracy of the benign and malignant tumors is 81.1%. If the accumulation of 201TlCl in the part of nodules remains on the delayed scintigraphy and the radioactivity in other parts of the thyroid gland disappears, the malignancy of the nodules would be suspected. On the other hand, in case the accumulation of 201TlCl on the delayed scintigraphy disappears or 201TlCl remains in the whole thyroid glands, including the nodular part, the benignancy of the nodule would be considered. |
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| Practice | Clinical medicine |
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| Keywords | Nodular goiter, 201TlCl scintigraphy, Early and delayed scintigraphy. |
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