| Japanese |
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| Title | 急性心筋梗塞症の99mTc-PYPピロリン酸シンチグラフィによる重症度評価に関する検討 |
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| Subtitle | 原著 |
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| Authors | 中島義治*, 福崎恒*, 前田和美**, 南地克美***, 紀田利***, 岡田敏男***, 今井直昭***, 山田重信***, 後藤武***, 吉田浩*** |
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| Authors(kana) | |
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| Organization | *神戸大学医学部第一内科, **神戸大学医療技術短期大学, ***兵庫県立姫路循環器病センター |
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| Journal | 核医学 |
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| Volume | 21 |
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| Number | 1 |
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| Page | 27-33 |
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| Year/Month | 1984/1 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」急性心筋梗塞症 (AMI) の重症度評価を行う目的にて, 73例の虚血性心疾患患者 [急性心筋梗塞症70例, (貫壁性梗塞63例, 心内膜下梗塞7例) , 不安定狭心症3例] を対象として, 99mTc-ピロリン酸 (PYP) シンチグラフィを施行した. 方法はAMI発症後平均3.5日に99mTc-PYP 15mCiを静注, 3時間後に撮像し, 心筋梗塞状態をpattern, intensity, sizeの3点から評価した. pattern, intensity, sizeの各分類はそれぞれ血清酵素値 (max. LDH) の上昇程度を反映し, 特にlocalized pattern, marked intensity, large sizeの集積を示す群はmax. LDH 3769±1052IU/lと最も高く, タリウムシンチグラフィではlarge defectを示し, RI左室駆出率は21±8%と著減を示した. 死亡例の8例中4例はmarked intensity, large sizeの広範集積を示し, この集積度を示す例は重症例であると考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | 99mTc-PYP myocardial scintigraphy, acute myocardial infarction, high risk cases. |
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| English |
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| Title | Technetium-99m Pyrophosphate Scintigraphy in Acute Myocardial Infarction in Special Reference to the Detection of High Risk Cases |
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| Subtitle | Original Articles |
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| Authors | Yoshiharu NAKASHIMA*, Hisashi FUKUZAKI*, Kazumi MAEDA**, Katsumi MINAMIJI***, Toru KIDA***, Toshio OKADA***, Naoaki IMAI***, Shigenobu YAMADA***, Takeshi GOTO***, Yutaka YOSHIDA*** |
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| Organization | *First Department of Internal Medicine, Kobe University, **School of Allied Medical Science, Kobe University, ***Hyogo Brain and Heart Center at Himeji |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 21 |
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| Number | 1 |
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| Page | 27-33 |
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| Year/Month | 1984/1 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] 99mTc-pyrophosphate (PYP) myocardial scintigraphy was performed in 73 patients admitted to the Coronary Care Unit. The time interval for imaging from the onset of acute myocardial infarction (AMI) was 3.5 days in an average. In addition, thallium-201 (Tl-201) myocardial scintigraphy and gated cardiac blood pool scintigraphy were performed. Findings of scintigram with 99mTc-PYP were graded according to the distribution pattern, intensity and size of myocardial uptake. Sensitivity of positive scintigram for AMI was 94% (59/63) . The group with localized pattern, marked intensity and large size showed highest value of serum maximum LDH (3,769+-1,052 IU/l, Mean+-S.D. ) and lowest value of radioisotope ejection fraction (21+-8%) . Fifty percent of dead patients (4/8) showed massive uptake in 99mTc-PYP myocardial scintigraphy. In conclusion, a localized pattern associated with marked intensity and large size is a useful indicator for assessing the severity of AMI. |
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| Practice | Clinical medicine |
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| Keywords | 99mTc-PYP myocardial scintigraphy, acute myocardial infarction, high risk cases. |
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