| Japanese |
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| Title | 糖尿病患者における胃排出機能 - 流動食を用いた核医学的胃排出機能検査法 - |
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| Subtitle | 原著 |
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| Authors | 多田明*, 小泉潔*, 油野民男*, 分校久志*, 利波紀久*, 久田欣一*, 荒木一郎**, 上野敏男** |
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| Authors(kana) | |
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| Organization | *金沢大学医学部核医学科, **第二内科 |
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| Journal | 核医学 |
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| Volume | 21 |
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| Number | 1 |
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| Page | 19-26 |
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| Year/Month | 1984/1 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」糖尿病患者21例を含む合計47例の患者に対し, Tc-99m Sn-colloid 200 uCiをよく混和した抗動食 (オクノソー) を投与し, 胃排出時間 (Gastric Emptying Time=GET) を測定した. 正常者9例のGETは62.5±7.7分であり, 平均±2 S.D. を正常範囲とすると, 47分から78分までが正常値であった. 糖尿病患者21例中14例には糖尿病性の合併症が認められたが, 3つ以上の合併症がある群ではGETは86.8±26.9分であり, 正常者, 合併症のない糖尿病患者のGETよりも有意に遅れていた. 一方合併症のない糖尿病患者では正常者よりも胃排出が早い傾向があった. GETと糖尿病患者の体格, 病歴, 治療方法, HbAlcとは相関が認められなかった. |
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| Practice | 臨床医学：一般 |
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| Keywords | gastric emptying study, semisolid test meal, diabetic mellitus. |
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| English |
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| Title | Gastric Emptying Time (GET) with Tc-99m-labeled Semisolid Meal in Diabetic Patients |
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| Subtitle | Original Articles |
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| Authors | Akira TADA*, Kiyoshi KOIZUMI*, Tamio ABURANO*, Hisashi BUNKO*, Norihisa TONAMI*, Kinichi HISADA*, Ichiro ARAKI**, Toshio UENO** |
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| Authors(kana) | |
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| Organization | *Department of Nuclear Medicine, Kanazawa University, **Second Internal Medicine, Kanazawa University |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 21 |
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| Number | 1 |
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| Page | 19-26 |
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| Year/Month | 1984/1 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Measurement of gastric emptying in diabetic gastroenteropathy is of interest because of the gastric atony that may produce signs and symptoms of visceral neuropathy. The purpose of this study is to present the result of GET measurements in diabetic patients. The correlation between GET and complications, fasting blood sugar (FBS) , duration of disease, age, sex, and HbA1c was evaluated. Included in this study were 21 diabetic patients. Fourteen patients had diabetic complications such as peripheral neuropathy, autonomic neuropathy, nephropathy and retinopathy. Following an overnight fast, semisolid test meal mixed with 200 uCi of Tc-99m Sn-colloid was ingested by the patients. In nine normal volunteers, the GET range previously established by this method in our institution was from 47 to 78 minutes (mean 62.5+-7.7) . In the patients vith diabetic complication, particulary with triopahy, GET was significantly prolonged compared to those of normal subjects and diabetic patients without complication. On the contrary, four out of seven patients without complications, showed rapid emptying than normal subjects. This rapid emptying may reveal the early stage of pathophysiological change in diabetics. No correlation between GET and FBS, duration of disease, age sex and HbA1c was seen. This test of radiolabeled semisolid meal was found to provide a convenient, safe and effective diagnostic tool to examine gastric emptying function in diabetic patients. |
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| Practice | Clinical medicine |
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| Keywords | gastric emptying study, semisolid test meal, diabetic mellitus. |
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