Japanese
Titleびまん性肺疾患における67Gaシンチグラムの検討 - 胸部X線像との対比 -
Subtitle原著
Authors伊藤新作*, 三上理一郎*, 龍神良忠*, 春日宏友*, 塩谷直久*, 宮崎隆治*, 成田亘啓*, 筒井重治**, 芝辻洋**, 浜田信夫**
Authors(kana)
Organization*奈良県立医科大学第二内科, **腫瘍放射線科
Journal核医学
Volume20
Number10
Page1459-1466
Year/Month1983/12
Article原著
Publisher日本核医学会
Abstract「要旨」腫瘍と感染症を除くびまん性肺疾患61例 (内訳 : 珪肺13例, 石綿肺11例, 特発性間質性肺炎9例, 膠原病による間質性肺炎4例, 過敏性肺炎2例, 肺門型サルコイドーシス9例, 肺門・肺野型および肺野型サルコイドーシス4例, ヒスティオサイトーシスX2例, びまん性汎細気管支炎7例) について, 肺野への67Ga集積の異常について検討した. 肺門型サルコイドーシス (9例中4例陽性) を除く他疾患の全例に陽性所見を呈し, 集積の程度は珪肺, 肺野型サルコイドーシスで高度, 石綿肺, 特発性間質性肺炎で中等度, びまん性汎細気管支炎, 肺門型サルコイドーシスで軽度であった. なお, 膠原病による間質性肺炎は特発性間質性肺炎よりやや高い傾向にあり, 過敏性肺炎では著しく高い例がみられた. 胸部X線像との比較では, 珪肺ではじん肺X線分類, 3, 4型が1, 2型に比して67Gaの集積が高かったが, 石綿肺では関係がみられなかった. 間質性肺炎では「肺線維症・X線分類」のI型とII型の間に関係がみられず, I型のうち, 粒状影の密度が高い例では67Gaの集積は高度, 密度の低い例で中等度〜軽度の集積がみられたがII型ではいずれも中等度であった. 67Gaシンチグラムは各種びまん性肺疾患の鑑別, ならびにX線写真では困難な活動性の判定に有用である.
Practice臨床医学:一般
Keywords67Ga-citrate scintigram, diffuse pulmonary disease, pneumoconiosis, interstitial pneumonia, sarcoidosis
English
TitleClinical Evaluation of 67Ga-citrate Scintigrams in Diffuse Pulmonary Diseases - Comparison with Radiological Findings
SubtitleOriginal Articles
AuthorsShinsaku ITO*, Riichiro MIKAMI*, Yoshitada RYUJIN*, Hirotomo KASUGA*, Naohisa SHIOYA*, Ryuji MIYAZAKI*, Nobuhiro NARITA*, Shigeharu TSUTSUI**, Hiroshi SHIBATSUJI**, Shinobu HAMADA**
Authors(kana)
Organization*The Second Department of Internal Medicine, **Oncological Radiology, Nara Medical University, Kashiwara
JournalThe Japanese Journal of nuclear medicine
Volume20
Number10
Page1459-1466
Year/Month1983/12
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] 67Ga uptake was studied in 61 cases of diffuse pulmonary diseases ; 13 silicosis (Si) , 11 asbestosis (As) , 9 idiopathic interstitial pneumonia (IIP) , 4 collagen disease (Col. IP) , 2 hypersensitivity pneumonia (HP) , 9 hilum type sarcoidosis (Sar・H) , 4 pulmonary type sarcoidosis (Sar・P) , 2 histiocytosis X (HX) , 7 diffuse panbronchiolitis (DPB) . High uptake was observed in patients with Si and Sar・P, moderate uptake in patients with Sar・H. Higher concentration of 67Ga was observed in Col. IP than in IIP. Remarkably high concentration of 67Ga was observed in one case of HP although we had examined only a couple of cases. In comparison to Japanese classification of radiographs of the pneumoconiosis, higher concentration of 67Ga was observed in Category 3 and 4 than in Category 1 and 2 as to the patients with Si, but no relationships were found in concentration among the patients with As. As to the patients with IIP 67Ga uptake was higher in radiological Type II (granular and ring-like shadow) than in radiological Type I (granular shadow) . Thus in the present contribution, 67Ga scintigram was proved to be useful in differential diagnosis and estimating the activity of every diffuse pulmonary disease, such activity is usually hard to be estimated by radiological findings.
PracticeClinical medicine
Keywords67Ga-citrate scintigram, diffuse pulmonary disease, pneumoconiosis, interstitial pneumonia, sarcoidosis

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