| Japanese |
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| Title | Thallium-201心筋灌流像によるDuchenne型進行性筋ジストロフィー症の心筋線維化病変の評価 |
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| Subtitle | 原著 |
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| Authors | 河合直樹*, 山本秀平*, 岡田充弘*, 岩瀬正嗣*, 都田裕之*, 横田充弘*, 外畑巌*, 稲垣春夫**, 安部哲太郎***, 三島厚*** |
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| Authors(kana) | |
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| Organization | *名古屋大学医学部第一内科, **トヨタ病院内科, ***名古屋大学附属病院中央放射線部 |
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| Journal | 核医学 |
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| Volume | 20 |
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| Number | 10 |
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| Page | 1433-1440 |
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| Year/Month | 1983/12 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」Tl-201心筋灌流像を用いて, 二次性心筋症をきたす代表的疾患の1つである進行性筋ジストロフィー症 (PMD) の心筋線維化病変の評価を行った. PMD19例を対象として, 安静時に正面, 左前斜位3方向および左側面の計5方向においてTl心筋像を撮像し, これを肉眼的に評価した. 対象19例中, 13例で明瞭な左室の灌流欠損がみられ, うち11例で灌流欠損は左室後側壁または後壁を含む領域にみられた. 灌流欠損の有無と骨格筋変性障害度あるいは胸部X線CTで評価された胸廓変形の程度との間には有意な関係はみられなかった. 心不全で死亡した2例ではTl心筋像上, 比較的広範囲な左室領域に灌流欠損がみられた. 2〜3年の間隔をおいてTl心筋像を2回記録した9例中7例ではこの間のTl心筋像の経年変化はほとんどみられないかあるいは軽度であった. Tl心筋像による本症の心筋線維化病変の非観血的評価は臨床的に有用と考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | thallium-201 myocardial perfusion imaging, Duchenne progressive muscular dystrophy, secondary cardiomyopathy, transmission computed tomography |
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| English |
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| Title | Evaluation of Myocardial Involvement in Duchenne Progressive Muscular Dystrophy with Thallium-201 Myocardial Perfusion Imaging |
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| Subtitle | Original Articles |
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| Authors | Naoki KAWAI*, Schuhei YAMAMOTO*, Mitsuhiro OKADA*, Masatsugu IWASE*, Hiroyuki MIYAKODA*, Mitsuhiro YOKOTA*, Iwao SOTOBATA*, Haruo INAGAKI**, Tetsutaro ABE***, Atsushi MISHIMA*** |
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| Authors(kana) | |
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| Organization | *First Department of Internal Medicine, Nagoya University School of Medicine, **Department of Internal Medicine, Toyota Hospital, ***Department of Radiology, Nagoya University Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 20 |
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| Number | 10 |
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| Page | 1433-1440 |
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| Year/Month | 1983/12 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Myocardial involvement in progressive muscular dystrophy of the Duchenne type was evaluated in 19 patients using thallium-201 myocardial perfusion imaging. The qualitative analysis was performed in anterior, 3 left anterior oblique and left lateral projection images by three experienced physicians. Distinct perfusion defects were shown in 13 patients, especially in LV posterolateral or posterior walls (11 patients) . There was no significant relationship between the presence of perfusion defects and the skeletal muscle changes or thoracic deformities assessed by transmission computed tomography. Slightly increased thallium-201 activity in RV free wall and lungs was shown in nine and one patient, respectively. The extensive perfusion defects were shown in 2 patients who died of congestive heart failure 1 to 2 years after the scintigraphic study. The myocardial scintigraphic changes were considered to be minimal in 7 of 9 patients who underwent two serial scintigraphic studies in 2 to 3 years. It was concluded that the thallium myocardial perfusion imaging was a useful clinical technique to evaluate the cardiomyopathy in Duchenne progressive muscular dystrophy. |
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| Practice | Clinical medicine |
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| Keywords | thallium-201 myocardial perfusion imaging, Duchenne progressive muscular dystrophy, secondary cardiomyopathy, transmission computed tomography |
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