| Japanese |
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| Title | 肺癌における67Ga-citrateシンチグラフィの臨床的有用性の再検討 - Log-likelihood-ratio法を用いて - |
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| Subtitle | 原著 |
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| Authors | 小須田茂*, 西村嘉裕**, 柳内登**, 青柳昭雄***, 遠藤雅裕****, 高木八重子****, 久保敦司****, 橋本省三**** |
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| Authors(kana) | |
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| Organization | *国立大蔵病院放射線科, **国立療養所晴嵐荘病院外科, ***内科, ****慶応義塾大学医学部放射線医学教室 |
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| Journal | 核医学 |
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| Volume | 20 |
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| Number | 9 |
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| Page | 1319-1328 |
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| Year/Month | 1983/11 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」 胸部X線写真上, 肺に異常陰影を有する患者78例を対象として, 肺癌の診断過程におけるガリウムシンチグラフィの有用性をLog-likelihood-ratio (LLR) 法によって評価した. ガリウムシンチグラムの読影前に, 胸部X線像 (背腹像, 側面像, 前額断層像) が読影され, その所見を参考にして同じ読影医によってガリウムシンチグラムが読影された. その結果, LLRの平均値は0.191±0.308であり, 47例 (60.3%) がLLR 0.00を示し, LLR 1.0以上を示した症例はわずか2例であった. 肺癌の診断過程におけるガリウムシンチグラフィのスクリーニング検査としての意義は少ないと思われる. しかし, ガリウムシンチグラフィは肺癌におけるN2 (縦隔リンパ節) の検索において, sensitivity 60.0%, specificity 88.2%を示し, ガリウムシンチグラフィはN2の検索に有用であると思われる. |
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| Practice | 臨床医学：一般 |
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| Keywords | 67Ga-citrate, lung cancer, log-likelihood-ratio, tumor scintigraphy |
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| English |
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| Title | Reassessment of the Clinical Usefulness of 67Ga-citrate Scanning in Lung Cancer Using a Log-likelihood-ratio Method |
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| Subtitle | Original Articles |
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| Authors | Shigeru KOSUDA*, Yoshihiro NISHIMURA**, Noboru YANAI**, Akio AOYAGI***, Masahiro ENDO****, Yaeko TAKAGI****, Atushi KUBO****, Shozo HASHIMOTO**** |
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| Authors(kana) | |
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| Organization | *Department of Radiology, Okura National Hospital, **Department of Surgery, and***Internal Medicine, Seiranso-Byoin National Sanatorium, ****Department of Radiology, Keio University School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 20 |
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| Number | 9 |
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| Page | 1319-1328 |
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| Year/Month | 1983/11 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] To reassess prospectively clinical usefulness of Ga-67 imaging in abnormal shadow on chest roentgenogram, 78 patients were scintigraphed after intravenous injection of 111MBq (3 mCi) of Ga-67 citrate. Before and after Ga-67 scanning, the same physician completed two questionnaires indicating his differential diagnosis, diagnostic confidence (expressed as a percentage) and therapeutic plan, referring chest roentgenograms (dorsoventral and lateral views) and chest roentgen tomograms (frontal projection only) . The impact of the imaging of the physician's diagnostic confidence was expressed as a log-likelihood-ratio (LLR) . The mean log-likelihood-ratio (LLR) for this series was 0.191+-0.308 (n=78) , with 47 out of 78 (60.3%) patients demonstrating a LLR, 0.00. In only two out of 78 (2.6%) patients, a LLR greater than 1.0 was achieved. These results reflect the little impact of Ga-67 scanning on the decision-making process for lung cancer. However, Ga-67 scanning may be useful for detecting N2 (mediastinal lymphnode) and determing of the staging in patients with lung cancer, indicating a sensitivity of 60.0% and a specificity of 88.2%. |
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| Practice | Clinical medicine |
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| Keywords | 67Ga-citrate, lung cancer, log-likelihood-ratio, tumor scintigraphy |
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